arterioles, capillaries, venules and veins play a major role. A certain amount of overlap with other chapters is unavoidable. Some vascular malformations are considered under nevi (Chap. 52), while the role of the vessels is also emphasized in allergic reactions ...
This chapter discusses diseases of the heart and blood-vessels correlated to the oral tissues. In rheumatic fever, the heart is affected by a systemic disease of the connective tissue. Rheumatic fever is a disease of children and young adults due indirectly to a poststreptococcal sensitization ...
Both blood vessels and nerves are vital channels to and from tissues. Recent genetic insights show that they have much more in common than was originally anticipated. They use similar signals and principles to differentiate, grow and navigate towards their targets. Moreover, the vascular and nervou...
related physiological processes. This would include early innate immune responses (inflammation), activation of thesympathetic nervous system, and stimulation of theCRHpathway, all of which are capable of producing negative health outcomes. Thus, the very processes to which they initially contribute, i...
Cardiovascular diseases are pathological conditions affecting the heart and/or blood vessels that is, the cardiovascular system. Featured Receptor activation via phase separation affects cardiac preservation quality A phenomenon of mineralocorticoid receptor phase separation exacerbates injury to mouse and...
Ferroptosis, a unique type of cell death, is characterized by iron-dependent accumulation and lipid peroxidation. It is closely related to multiple biological processes, including iron metabolism, polyunsaturated fatty acid metabolism, and the biosynthes
Blood tests.A lab can check your blood to see if it has high levels of substances that cause inflammation, which could be damaging your heart valves. Angiogram.This test is simply an X-ray of your blood vessels. Before the exam, you will have a special dye injected into your body, whic...
Ferroptosis, a unique type of cell death, is characterized by iron-dependent accumulation and lipid peroxidation. It is closely related to multiple biological processes, including iron metabolism, polyunsaturated fatty acid metabolism, and the biosynthes
late-stage neuropsychiatric assets.The company’s small molecule product candidates represent three distinct therapeutic strategies—calcitonin gene-related peptide (CGRP) receptor antagonists, glutamate modulators, and myeloperoxidase inhibitors—with potential to bring new treatment approaches to patients in nee...
Fig. 1. Schematic representation of the proposed sequence of events moving from age-related alterations to multimorbidity. The multi-system loss of reserve and function has its origin in the biological determinants of the ageing process, and increases susceptibility to chronic diseases. This phenomenon...