The cells of the connective tissues contain lysosomes with enzymes capable of degrading intercellular substances (collagen, elastin, proteoglycans) and release their enzymes in membrane-bound or in free form into their intercellular substance. In this way extracellularly located lysosomes (= matrix ...
suggested that the histopathological connective tissue changes found in SLE were common to the 'obscure maladies that collectively are called diseases of the connective tissue or collagen diseases' [41], little did he know that a cure for such diseases might also be found within connective tissues...
Connective TissuesDiseases Perfect discrimination between Connective Tissue Diseases. ELISASMC TechnologyIFA Connective Tissue Diseases Published 11.29.2024 - Last update 01.02.2025 AboutConnective Tissues Diseases Autoimmune connective tissue diseases (CTD) are characterized by spontaneous overactivity of the imm...
Diseases in which inflammation or weakness of collagen tends to occur are also referred to as collagen diseases. Collagenvascular diseaseis a somewhat antiquated term used to describe diseases of the connective tissues that typically include diseases that can be (but are not necessarily) associated wi...
About Connective Tissues Diseases Autoimmune connective tissue diseases (CTD) are characterized by spontaneous overactivity of the immune system resulting in the production of antibodies against several autoantigens. The evolution of the disease can be rapid or slow and start from subtle abnormalities ...
This category reviews all of these entities, but also includes other diseases that affect the connective tissues with relevance to dermatology. A number of non-specific clinical findings may suggest the possibility of autoimmune connective tissue disease. These include: Raynaud’s phenomenon, non-scar...
Connective tissue diseases (CTDs) represent a heterogenous group of disorders characterized by pathological features of chronic inflammation of blood vessels and connective tissues. Inflammation in multiple organs can lead to a variety of symptoms, such as musculoskeletal stiffness, pain, Raynaud phenomenon...
13. Diseases of the Musculoskeletal System and Connective Tissue (710-739) The following fifth-digit subclassification is for use with categories 711-712, 715-716, 718-719, and 730: 0 site unspecified 1 shoulder region Acromioclavicular joint(s) Glenohumeral joint(s) Sternoclavicular joint(s) ...
immunologic disorder characterized by excessive fibrosis in multiple tissues, obliterative vascular disease, and autoimmunity-visceral involvement of GI tract, lungs, kidneys, heart and skeletal muscles diffuse systemic sclerosis initial widespread skin involvement, with rapid progression and early visceral invo...
In clinical trials, the exposure of patients with renal impairment to Gd-based contrast agent may lead to the fibrosis of the connective tissue in the skin and systemic tissues, known as nephrogenic systemic fibrosis (NSF). To dispel this concern, the skin tissues of rats were obtained for hi...