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immunocompromised mice to establish a non-alcoholic fatty liver disease model, with or without nitrate supplementation, to examine relevant indicators.In VitroExperiments: Stable overexpression of Sialin was established in macrophages, followed by exposure to differentiation stimuli, to measure immune-...
Cause: Lyme disease is caused by Borrelia burgdorferi bacteria, which is transmitted to humans via bites from infected blacklegged ticks, also known as deer ticks. In Animals: Disease prevalence in wildlife is unknown, though white-footed mice are the main reservoir for Lyme dis...
They studied mice that had been deliberately infected with either one of the parasites that cause the diseases—B. microtiin the case of babesiosis andB. burgdorferifor Lyme—or both at the same time. They allowed ticks to feed on the mice, and then each week over a six-week period they...
That hantavirus is spread by deer mice. In the U.S., however, no person-to-person transmission of this virus has been reported to date, the CDC says. Symptoms include fever, chills, myalgia, headache and gastrointestinal issues, among other features. And although this disease is rare, the...
Notably, intercellular communication that EVs mediate can be influenced by the inducible factors of atherosclerosis. A recent study demonstrated an increase in the expression level of miR-27b-3p in serum exosomes and exosomes in the visceral adipocytes of obese mice and patients with atherosclerosis. ...
In ALS and SBMA mice models, HSPB8 induction in muscle is accom- panied by the induction of several other genes involved in the autophagic clearance of misfolded proteins, like p62/SQSTM1, LC3, BAG3 and BAG11,21,22. HSPB8 also participates in the clearance of other misfolded proteins ...
16.4A). This resulted in 42 people contracting Sin Nombre virus, a previously unrecognized hantavirus carried by deer mice. Sixty-two percent of the individuals that contracted Sin Nombre virus died of hantavirus pulmonary syndrome. Download: Download full-size image Figure 16.4. Factors in the ...
(S.mansoni) led to changes in the composition and diversity of gut microbiota in mice [136]. Some bacterial species, such as Planctomycetes and Verrucomicrobia, showed significant alterations in abundance following infection, suggesting their potential involvement in interactions between the host and ...
Indeed, mice that are LAP deficient develop a SLE-like disease, characterized by increased cytokine and autoantibody levels in the serum and decreased clearance of dead cells [52]. Exposing these animals to dead cells exacerbate the disease phenotype [52]. Interestingly, the same does not happen...