Clinical diagnosis is typically made through a process that starts with identifying initial findings and noting the past medical history of the patient and ends with a diagnosis or unresolved differential diagnoses1,2. In practice, the sequence of steps one clinician follows may be very different fr...
“dopamine”—a chemical that works as aneurotransmitterfor controlling movements in different parts of the body. The degenerative process starts from the base of the brain, leading to the destruction ofolfactory bulbs, followed by the lowerbrain stemand subsequently substantia nigra and midbrain[18...
Alzheimer’s disease (AD) is the most common neurodegenerative disease that currently lacks available effective therapy. Thus, identifying novel molecular biomarkers for diagnosis and treatment of AD is urgently demanded. In this study, we exploited tools and concepts of the emerging research area of...
a whole and its members individually. The lived experiences are recounted by the Mother (first author) and have been further explored through the method of co-constructed autoethnography. Metaphors have been used to help understand the findings. Our findings show that each individual QoL not only ...
Inflammatory bowel disease (IBD) is a chronic relapsing and remitting inflammatory disorder of the small intestine and colon. Ulcerative colitis (UC) and Crohn’s disease (CD) are the two main types of IBD. UC is described through inflammation that is restricted to the colon. It starts in th...
Eye disease, any of the diseases or disorders that affect the human eye. Learn about the more common types of diseases of the eye and its associated structures, the methods used in examination and diagnosis, and the factors that determine treatment and p
This progressive disease occurs when your heart’s ability to pump blood starts to decline. CAD, heart attack, diabetes,obesity, and high blood pressure are among the common causes of heart failure. As your heart can no longer pump as well as it used to, the blood that would normally cycl...
They found that patients treated relatively recently had lower ESR values and that those cases with recent onset RA, stratified by quartiles of ESR, maintained their position over time. There is often talk of ‘burnt-out’ rheumatoid, implying that RA patients reach a stage in their disease ...
CSF biomarkers for the early diagnosis of Alzheimer's disease in a routine clinical setting - The first Portuguese study Introduction: Alzheimer's disease (AD) is the most common neurodegenerative disorder, and it is known that the underlying pathology starts years before clinical symptoms. Therefore...
The training starts with the weights trained using the self-supervised inpainting method. The last layer is changed to its original layer instead of the replaced convolutional layer. By learning features from image inpainting, the model can learn features that are closer related to image segmentation...