A primary goal of human genetics is to identify DNA sequence variants that influence biomedical traits, particularly those related to the onset and progression of human disease. Over the past 25 years, progress in realizing this objective has been transformed by advances in technology, foundational ...
Several decades ago, Christopher Boorse formulated an influential statistical theory of normative biological functions but it has often been claimed that h... Kraemer,M Daniel - 《Biology & Philosophy》 被引量: 13发表: 2013年 An SIR Epidemic Disease Model with Vertical Transmission and Pulse Vacci...
changes in expression detected by revTWMR do not necessarily represent the consequence of the disease but can also reflect the consequences of a genetic predisposition to that disease. Therefore, identified genes might represent early biomarkers of disease (predisposition) and modulation of their...
Chemical Residues in Muscle Foods Reports from the 19th century and earlier indicate that adulteration of foods with fillers, coloring agents, and preservatives was widespread. Some of these adulterants such as copper sulfate and boric acid were quite toxic by present-da... WA Moats - Springer US...
A collaborative network analysis revealed that the United States, Japan and mainland China were the most influential countries in this field. The University of California system contributed the most publications and the journal with the most publications was Circulation. JW Newburger was an ...
Update History References 1 What Is Chronic Kidney Disease? Summary and Quick Facts for Chronic Kidney Disease About 15% of adults in the United States, or 37 million people, suffer from chronic kidney disease (CKD). However, 90% of these individuals do not know that they have this poten...
“Research, along with the budget, has been steadily increasing over the last 20 years,” Melov says. “It’s not a lack of money or a semantic thing of aging as a disease or not a disease that’s holding the field back.” Rather, what the field needs to move forward, Melov says...
in which a pathogenic variant has been determined are caused by variants in the amyloid precursor protein (APP) or the presenilin genes (PSEN1,PSEN2) encoding the catalytic subunit of the ɣ-secretase complex that generates Aβ peptides via cleavage of APP. Interestingly, it has been estimated...
counts of the top ten co-cited academic journals were distributed around an average of 2000, indicating a substantial level of citations and recognition in the field. However, it is worth noting that while prolific journals frequently represent this area’s research history and status quo, highly...
In other cases, these conditions are a common disease presenting in a less common manner. Dr. Hardeep Singh, a renowned expert on diagnostic errors and a reviewer for the Institute of Medicine’s (IOM) influential report “Improving Diagnosis in Health Care,” has estimated that one in 20...