Bones are constantly undergoing remodeling due to bone being reabsorbed. This bone remodeling occurs via the action of several hormones such as parathyroid hormone growth hormone and calcitonin.Answer and Explanation: Become a member and unlock all Study Answers Start today. Try it no...
BPs are antiresorptive drugs utilized clinically in bone-related disorders that involve excessive bone resorption, including osteoporosis, metastatic bone disease and Paget's disease. The anti-resorptive potency of BPs may be broadly classified on the basis of whether or not they contain a nitr...
Bacteria may produce a toxin or poison that can affect a body site distant from where the bacterial replication occurs, such as in tetanus. Bacteria may also initiate an excessive immune response, producing damage to other body tissues away from the site of infection (e.g., acute rheumatic ...
Subacute thyroiditis: Inflammation of the thyroid that causes the gland to “leak” excess hormones. This leads to temporary hyperthyroidism that generally lasts a few weeks but may persist for months. Pituitary gland malfunctions or cancerous growths in the thyroid gland: In rare cases, these ca...
Osteoclasts degrade the bone matrix to release stored cytokines and growth factors (e.g., transforming growth factor-beta, TGF-β) that, in turn, support MM survival and growth2,3,5,6,7,8,9,10. MM cells also suppress osteoblast maturation, thus tipping the balance towards excessive bone ...
Vitamin K is essential for the production of clotting proteins. As a result, vitamin K deficiency causes ableedingtendency among persons with celiac disease. Vitamin Dis essential for the absorption of calcium, which is required for appropriate bone growth. As a result, vitamin Ddeficiency may cau...
96 Moreover, diabetes causes a more than two-fold induction of more than 70 genes that directly or indirectly regulate apoptosis during inflammation-induced bone injury and that significantly enhance caspase-8, -9 and -3 activity.97 A significant effect on bone, which was induced by cell death...
The use of gallium salts for preventing or treating disorders associated with excessive loss of calcium from bone in an individual is disclosed. More particularly the use of gallium salts in the prevention or treatment of hypercalcemia associated with cancer or hyperthyroidism and the use of gallium...
it is hypothesized that an underlyinggenetic mutationinvolving regulation of the immune system predisposes an individual to the development of CD or UC. When that individual is exposed to a dietary or infectious antigenic trigger for the disease, excessive and aberrant intestinal inflammation results. ...
Nevertheless, culture and biochemical characterization are no longer frequently used in routine medical practice simply because of the modest expense and minimal time associated with growth of bacteria that can be cultivated overnight in the laboratory media (Bartlett, 2011). Due to the typical low ...