AD is named after Dr. Alois Alzheimer, a German doctor. In 1906, Dr. Alzheimer noticed changes in the brain tissue of a woman who had died of an unusual mental illness. He found abnormal clumps. Scientists also have found other brain changes i...
The traditional introgression of resistance genes into resistant cultivars can take more than ten years starting from making crosses between the recurrent parents and the resistance donor parents. Fortunately, with the development of molecular marker technology, especially with the sequencing of the soybean...
The starting dose of levothyroxine in primary hypothyroidism treatment: a prospective, randomized, double-blind trial. Arch. Intern. Med. 165, 1714–1720 (2005). Article CAS PubMed Google Scholar Hoang, T. D., Olsen, C. H., Mai, V. Q., Clyde, P. W. & Shakir, M. K. Desiccated...
In the same family, cytomegalovirus (CMV) has emerged as a common cause of hypertensive anterior uveitis [44], and also causes a characteristic retinitis in immunodeficient individuals, leading to a substantial visual burden especially in poor countries [37]. These infections are treatable with a ...
However, starting with GBD 2019, estimates for the burden of NAFLD are being provided. Previously, the GBD only provided estimates for liver complications (cirrhosis and liver cancer) related to NAFLD and did not provide data for the actual prevalence of NAFLD.19 As such, with the use of the...
The SARS-CoV-2 pandemic is currently leading to increasing numbers of COVID-19 patients all over the world. Clinical presentations range from asymptomatic, mild respiratory tract infection, to severe cases with acute respiratory distress syndrome, respir
The longest open reading frame associated with each gene was included in the starting set. Curated mRNA sequences from the RefSeq NCBI database and genomic sequences for the four model organisms (chimpanzee, mouse, rat and dog) and chicken (outgroup) were extracted from GenBank (accessed in ...
Age at starting to smoke, total packyears smoked, and current smoking status are predictive of COPD mortality. Not all smokers develop clinically significant COPD, which suggests that genetic factors must modify each individual's risk9. and possibly the priming of the immune system23,24. ...
Maternal polygenic risk for UC and Crohn’s was associated with a higher autism factor mean score in the child (UC:βPRS = 0.02; 95%CIs: 0.003 to 0.05;P = 0.03; Crohn’s:βPRS = 0.03; 95%CIs: 0.01 to 0.05;P = 0.004). Similar results were found across otherP-...
used denoising AEs derived from the transcriptomics of Pseudomonas aeruginosa and discovered a representation where each node coincided with known biological pathways17. Chen et al. used cancer data and showed that starting from pathways represented as a priori defined hidden nodes, allowed the ...