Behavioral studies showed significant cognitive dysfunctions similar to those of Autism spectrum disorder (ASD) and Alzheimer's disease (AD). A comparative analysis of the SNO-proteome of SA-treated mice with two transgenic mouse strains, models of ASD and AD, showed molecular ...
transplant– v. medical :to move an organ or other part (such as a cell) from something and put it into something else disorder– n. medical :a physical or mental condition that is not normal or healthy uniquely– ...
syndromic and non-syndromic autism. We discuss how modeling the central nervous system cells in a dish may help to reach a better understanding of ASD pathology and variability, as well as personalize their treatment. We would like to thank the support of the agency FAPESP (2011/20683-0, 09...
early childhood, puberty and adulthood)9and in splicing10. Reasons for sex-biased gene expression for some autosomal genes may be related to the presence of androgen or estrogen hormone response elements11. Sex-biased gene expression likely contributes to differences ...
One idea was that the female brain at baseline may be more similar to an Alzheimer's brain, so it is easier for them to shift into that state (likewise, males may be more similar to autism). To test this, we examined gene expression differences between brains of biological males and ...
Mouse modeling shows neurodevelopmental defects associated with complex congenital heart disease can arise independent of the cardiac defects, with microcephaly and autism occurring with incomplete penetrance subject to epigenetic regulation. George C. Gabriel ...
Following reports of lymphocytic colitis and small bowel enteropathy in children with regressive autism, we aimed to see whether similar ch... F Torrente,A Anthony,RB Heuschkel,... - 《American Journal of Gastroenterology》 被引量: 157发表: 2004年 Measles Vaccines controversy has recently been ...
Progress in understanding the genetic etiology of autism spectrum disorders (ASD) has fueled remarkable advances in our understanding of its potential neurobiological mechanisms. Yet, at the same time, these findings highlight extraordinary causal divers
et al. Prenatal air pollution influences neurodevelopment and behavior in autism spectrum disorder by modulating mitochondrial physiology. Mol. Psychiatry 26, 1561–1577 (2021). This study shows that long-term changes in mitochondrial function partially mediate the association between prenatal PM2.5 ...
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