Many studies in the past 20 years have identified a contribution of inflammation and immune mechanisms to the pathophysiology of hypertension. Innate and adaptive immunity participate in this process. Among innate immune cells, macrophages and monocytes as well as dendritic cells, myeloid-derived ...
Kidney injuries caused by agents, drugs, or preparations used in alternative medicine consist of ATN or toxicity (e.g., Fanconi's syndrome), acute interstitial nephritis, papillary necrosis, hypertension, kidney stones, urinary retention, chronic tubulointerstitial nephritis with fibrosis, urinary tract...
Cardiovascular diseases remain a major cause of destruction of human health worldwide.1In the worldwide, especially China and India have the highest burden of cardiovascular disease.2It includes coronary heart disease, hypertension, heart failure, vascular calcification and so on. In the Framingham He...
The majority of clinical trials for systemic sclerosis (SSc) focus on skin disease, interstitial lung disease (ILD), or pulmonary arterial hypertension, with modified Rodnan skin score (MRSS), forced vital capacity and 6-min walk distance being the primary clinical end points assessed, respectively...
Ureteral compression is associated with retroperitoneal extension of the phlegmonous inflammatory process involving the terminal ileum and cecum, and may result in hydronephrosis severe enough to cause hypertension.[47] 参考译文:患有IBD的患者的泌尿系统表现可能包括输尿管结石、肠膀胱瘘、膀胱周围感染、肾...
Key systems that are important in the development of hypertension and cardiovascular disease (CVD), including the sympathetic nervous system, the renin–angiotensin–aldosterone system and the immune system, are differentially activated in males and females. Biological age also contributes to sexual ...
4Diseaseistheunhealthystateofabodypart,aphysiologicsystem,orthebodyasawhole;thereisadisorderedstructureorfunction.Diseaseoftenbeginsatthecellularlevel.Anabnormalgene,acquiredthroughone’sheredityormutated,oraltered,byanenvironmentalfactorcanstartthediseaseprocess.Cancer,forexample,beginswithuncontrolledgrowthofcellswhen...
Many of these conditions are precursors to more severe diseases with higher-intensity care needs. Our research shows, for example, that 71% of patients with heart failure have hypertension, 53% have hyperlipidemia, and 37% have diabetes.17 Given the provider loyalty...
31. Olivier M, Hsiung CA, Chuang LM, Ho LT, Ting CT, Bustos VI, Lee TM, De Witte A, Chen YD, Olshen R, Rodriguez B, Wen CC, Cox DR: Single nucleotide polymorphisms in protein tyrosine phosphatase 1b (PTPN1) are associated with essential hypertension and obesity. Hum Mol Genet 2004...
Benign intracranial hypertension(e.g., pseudotumor cerebri,papilledema, dural sinus thrombosis) ▪ Organic psychiatric disturbances (e.g., psychoses, depression, dementia) Several of these manifestations may occur simultaneously. The most commonCNSdisorder at presentation ismeningoencephalitiswith headache,...