Disease Ontology:人类疾病分类数据库 查看原文 DisGeNet:疾病相关的基因与突变位点数据库 欢迎关注”生信修炼手册”! DisGeNet是一个专门收录人类疾病相关的基因与突变位点信息的数据库,对应的文章发表在NucleicAcidsResearch上,链接如下...突变与疾病关联的数据库,比如ClinVar, GWASDB等, 同时通过机器学习的方法从文献中...
参考数据库有:Disease,Ontology,MeSH,Gene Ontology,GWAS Catalog,KEGG,Uniprot,所以信息会很全面,大家快去围观吧!数据库网址:http://easybioai.com/sc2disease/ Fig 1|网站首页图 在网站首页右侧将有数据的疾病都已展示出来了,包括肿瘤和非肿瘤疾病的共22种,点击选择对应的疾病可了解,其中有每个疾病的详细信息包括...
4. A Bidirectional-Based Spreading Activation Method for Human Diseases Relatedness Detection Using Disease Ontology [C] . Said Fathalla, Yaman Kannot International conference on computational collective intelligence . 2017 机译:基于疾病本体的基于双向传播激活方法的人类疾病相关性检测 5. Computational ...
in rats and mice causes a reversible detachment and synaptic uncoupling between the hcs and the ganglion neurons. here, we used this paradigm to study the global changes in gene expression in vestibular ganglia using rna-seq. comparative gene ontology and pathway analyses of the data from both ...
AD研发涉及的靶点覆盖几乎所有CADRO(常见默病致病假说,Common Alzheimer’s Disease Research Ontology)类别,除Aβ,其它靶点集中度相对分散。值得注意的是,管线中约37%的候选药物是已批准用于其他适应症的药物适应症拓展。 一些思考 由于病因未明,阿尔茨海默病被称为医药界的“黑洞”,药物的研发失败率高达99.6%,远高...
The results of phospho-proteomics and ontology analysis indicated that knockdown of OSGIN1 led to reduced propagation of the MKK3/6-p38 signaling axis. Conclusions We propose that OSGIN1 modulates microtubule dynamics by enhancing DYRK1A-mediated phosphorylation of TUBB3 at serine 172. Moreover, ...
在miR2Disease数据库中他们使用的是由专业的医学词汇(即UMLS系统,参见http://diseaseontology. sourceforge.net/)来命名的疾病名称,这样便于用户搜索和分析资料。数据库中的每一条记录都包含详细的 microRNA与疾病之间的关联信息、microRNAID号、相关疾病名称、患病时microRNA表达模式(上调还是 下调)介绍、microRNA表达...
(or query) Q and a DAML-S ontology T of services,we want to compute the best combinations of Web services that satisfy us such us possible the outputs of the request Q and that require as little as possible of the inputs that are not provided in the description of Q. 正在翻译,请...
APIs: application programming interfaces; circRNA: circular RNA; ECO: Evidence & Conclusion Ontology; EFO: Experimental Factor Ontology; FDR: false discovery rate; GO: Gene Ontology; GWAS: genome wide association studies; HPO: Human Phenotype Ontology; ICGC: International Cancer Genome Consortium; lnc...