10Stressadverselyaffectstheentirebody,itreducestheabilityoftheimmunesystemtocounteractdisease.Stresscausesseveraldiseasesofthegastrointestinalsystemsuchaspepticulcersandulcerativecolitis.Italsoaggravatesrespiratoryailments—asthma,forexample—andotherallergicconditions.Ifthecauseofadiseaseisnotknown,itissaidtobeidiopathic.11...
Inflammatory bowel disease (IBD) is an idiopathic chronic inflammatory disease of the gastrointestinal system. The spectrum is of predominantly two types, ... R Prashanth,S Tagore,RJ Pradeep - 《Journal of Inflammation Research》 被引量: 6发表: 2018年 Anti-Tumor Necrosis Factor Therapy in Inflamm...
It mentions the organs involved in the gastrointestinal (GI) tract; including the mouth, stomach, and small and large intestines, and the digestive system; including salivary glands, liver and pancreas. It explores the process of digestion, from mastication to the elimination of waste from the ...
Lymphatics perform essential transport and immune regulatory functions to maintain homeostasis in the gastrointestinal (GI) system. Although blood and lymphatic vessels function as parallel and integrated systems, our understanding of lymphatic structure, regulation and functioning lags far behind that of th...
Elucidation of human disease similarities has emerged as an active research area, which is highly relevant to etiology, disease classification, and drug repositioning. In pioneer studies, disease similarity was commonly estimated according to clinical ma
For example, the SNP rs2670660 protects against Celiac Disease in the gastrointestinal system; however, this gain-of-function mutation is also associated with the overactivation of the NLRP1 inflammasome in autoimmune disease (Alkhateeb et al., 2013; Jin et al., 2007b; Pontillo et al., 2011,...
Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are chronic, relapsing inflammatory condition of the gastrointestinal tract. CD and UC have distinct pathologic and clinical characteristics and despite the extensive amount of research conducted over the pas...
The taxonomic composition and functional characteristics of the microbiome may allow individuals to be categorized into different microbial patterns, called enterotypes, in the gastrointestinal tract. Although low-level taxonomy varies substantially among individuals, higher-level taxonomy and functional character...
Human disease - Causes, Pathogens, Symptoms: The search for the causes (etiologies) of human diseases goes back to antiquity. Hippocrates, a Greek physician of the 4th and 5th centuries bce, is credited with being the first to adopt the concept that dise
Evolution has endowed the gastrointestinal tract with its own dedicated nervous system. In mammalians, the enteric nervous system (ENS) consists of millions of neurons and glial cells that are organized into interconnected ganglia embedded within the gut wall. The ENS has the ability to autonomously...