Parkinson’s disease (PD) and cardio-cerebrovascular diseases are related, according to earlier studies, but these studies have some controversy. Our aim was to assess the impact of PD on cardiocerebrovascular diseases using a Mendelian randomization (MR
Article CAS PubMed Google Scholar Netea, M. G., Quintin, J. & Van Der Meer, J. W. M. Trained immunity: a memory for innate host defense. Cell Host Microbe 9, 355–361 (2011). This article describes the memory features of the innate immune system and proposes the term ‘trained ...
Elucidation of human disease similarities has emerged as an active research area, which is highly relevant to etiology, disease classification, and drug repositioning. In pioneer studies, disease similarity was commonly estimated according to clinical ma
Deep brain stimulation of the nucleus basalis of Meynert in Alzheimer’s dementia. Mol Psychiatry. 2015;20(3):353-360.PubMedGoogle ScholarCrossref 15. Turnbull IM, McGeer PL, Beattie L, Calne D, Pate B. Stimulation of the basal nucleus of Meynert in senile dementia of Alzheimer’s type...
ArticleCASPubMedPubMed CentralGoogle Scholar Bourre JM, Pascal G, Durand G, Masson M, Dumont O, Piciotti M (1984) Alterations in the fatty acid composition of ratbrain cells (neurons, astrocytes, and oligodendrocytes) and of subcellular fractions (myelin and synaptosomes) induced by a diet dev...
Therefore, the purpose of the current study was to evaluate the long-term prognostic value of NT-proBNP in Chinese patients with SCAD who have received PCI treatment. METHODS Study Design This study is an observational, prospective, single‑center study, which enrolled and collected data from...
Neurodegeneration, known as the progressive loss of neurons in terms of their structure and function, is the principal pathophysiological change found in t
Can the brain be protected through exercise? lessons from an animal model of parkinsonism. Exp Neurol. 2003;184(1):31-39.PubMedGoogle ScholarCrossref 5. Zigmond MJ, Smeyne RJ. Exercise: is it a neuroprotective and if so, how does it work? Parkinsonism Relat Disord. 2014;20(suppl 1...
indicating KBTBD4 insertion mutations as the primary genetic driver. Delineating the role of KBTBD4 mutations thus offers significant opportunities to understand tumour pathogenesis and to exploit the underpinning mechanisms therapeutically. Here, we show a novel mechanism in cancer pathogenesis whereby ind...
L. The amyloid precursor protein of Alzheimer disease in human brain and blood. J. Leukoc. Biol. 66, 567–574 (1999). Article CAS PubMed Google Scholar Toledo, J. et al. Factors affecting Aβ plasma levels and their utility as biomarkers in ADNI. Acta Neuropathol. 122, 401–413 (...