As will be seen, it is relatively easy to define a state of liver disease (hepatopathy) but it is difficult and often impossible to identify the precise causative agent. Although the pathology of the condition can be defined in histopathological terms, it is rarely indicative of the exact caus...
The middle ear relies in part on fully functioning ciliated epithelial cells and mucus-producing goblet cells for clearance of fluid and debris through the auditory tube. Thus abnormal cilia equates to abnormal auditory tube clearance. Macroscopic lesions include bilateral mucopurulent rhinitis, sinus...
In ontogenesis, EDNRB is expressed in the neu- ral tube before the initiation of NCC migration and continues to be expressed by ENS precursors as they begin to migrate (98). EDN3 and Endothelin Converting Enzyme 1 (ECE1) are expressed by the mesenchyme surrounding the neural tube, along ...
8c) primarily from the auditory cortex19, was spared from plaque attenuation in ExN-Bace1cKO;AD mice. In fact, immunolabeling of 5×FAD brain slices with the human APP-specific antibody, 1D1, revealed that human APP reactivity in neuronal soma is almost restricted to the cortex (Extended ...
Hearing loss is one of the leading causes of disability in Canada and worldwide, with more than one million Canadians enduring a hearing-related disability. Meniere’s disease (MD) is a chronic condition of the inner ear, manifesting as a triad of disabling symptoms, including attacks of verti...
auditory and cognitive processing. Methods: 130 participants, (mean 76.4±7.3 years; 65% women) of the Rancho Bernardo Study of Healthy Aging had a screening audiogram in 2003-2005 and brain magnetic resonance imaging in 2014-2016. Hearing ability was defined as the average pure tone threshold ...
Cues are the most well-known and widely studied behavioral approaches for ameliorating FOG. Cue is defined as using external temporal or spatial stimuli to facilitate movement (gait) initiation and continuation [159]. Cues are classified into visual, auditory or somatosensory cue based on delivery ...
C3 complement protein is one of the most characteristic and highly upregulated genes in A1 astrocytes and is not expressed by ischemic A2 reactive astrocytes, broadly used as a key marker of A1 astrocytes, which are demonstrated not only in diseased tissue from patients with PD, but also AD,...
SNHL occurs in 77% of patients probably due to demyelination of auditory nerve. Out of 40 patients reported [85,86], only one survived until 19 years old [85]. Zellweger Spectrum disorder (ZSD)is aperoxisomal disorderdefined as defects in PEX genes [87] and are grouped as (from more...
Self-care is defined e.g. by the UK Department of Health as “the activities that enable people to deal with the impact of a long term condition on their daily lives, dealing with the emotional changes, adherence to treatment regimes, and maintaining those things that are important to them...