It has been difficult for clinicians to recognize that this condition is primarily due to sensitization of mesenteric T lymphocytes to wheat protein (gluten) in genetically predisposed (DQ2+) individuals. On contact with dietary-derived gluten in the upper intestine, these sensitized T lymphocytes ...
1.Asymptomatic=a-+symptom+-(at)ic无症状的notshowinganysymptomsofthedisease,whetherthediseaseispresentornot.2.Anemia=an-+-emia(=hem+-ia(G.):condition):bloodcondition贫血areductioninthequantityoftheoxygen-carryingpigmenthemoglobinintheblood.3.Amorphous=a-+morph(G.):shape,form+-ous(L.):pertainingto...
Small Intestinal Diarrhea Indications for Intestinal Biopsies 小肠肠活活检检的的适适应应症症 小 1. Chronic GI problems 慢性胃肠道疾病 + poor clinical condition 临床情况较差 2. Chronic GI problems + inadequate response to diagnostic treatment trials 诊断性治疗无明显效果 3. Focal ...
The interaction of gliadin (a specific gluten present in certain grain products) with the lining of the small intestine is critical in the development of celiac disease. When people with celiac disease eat foods containing gluten, gliadin is identified by the immune system as a threat. As a re...
Celiac disease remains a challenging condition because of a steady increase in knowledge tackling its pathophysiology, diagnosis, management, and possible therapeutic options. A major milestone in the history of celiac disease was the identification of t
Bacteriacan survive within the body but outside individual cells. Some bacteria, classified asaerobes, require oxygen for growth, while others, such as those normally found in thesmall intestineof healthy persons, grow only in the absence of oxygen and, therefore, are calledanaerobes. Most bacter...
Celiac disease is an inflammatory immune disorder that occurs when genetically susceptible individuals eat gluten, a protein in wheat, barley, and rye. The immune system damages the lining of the small intestine, which can cause nutrient malabsorption and symptoms ranging from diarrhea and constipation...
Celiac disease damages the inner lining of the small intestine, and that may lead to difficulty digesting lactose, a sugar found in milk and milk products. Following a gluten-free diet allows the intestine to recover, and people with celiac disease may discover that they are able to digest la...
the severity of inflammation, anemia, or hypoproteinemia in the host; and the overall condition of the host. Whipworm infestation is diagnosed by the presence of barrel-shaped, thick-walled eggs with bipolar plugs on fecal flotation. Adult worms intermittently release eggs; therefore, negative res...
the HLA region are well established, while variants outside of the HLA region have recently been identified. These variants are beginning to enhance our understanding of the immunology of the condition. This review focuses on the immunological pathogenesis of coeliac disease with special reference to...