What are the symptoms of brittle bone disease? What is the medical term for brittle bone disease? Which vitamin should be taken along with a calcium supplement to help mitigate the rate of osteoporosis? What vitamin deficiency is caused by alcoholism?
Systemic autoinflammatory diseases are driven by abnormal activation of innate immunity1. Herein we describe a new disease caused by high-penetrance heterozygous germline mutations inTNFAIP3, which encodes the NF-κB regulatory protein A20, in six unrelated families with early-onset systemic inflammation...
the disease may be caused by some agent external to the organism, such as a chemical that is atoxicagent. In this case the disease is noncommunicable; that is, it affects only the individual organism exposed to it. The external agent may be itself a living organism capable of multiplying ...
A heart attack is cell death of heart muscle caused by lack of blood flow with oxygen deprivation. AS previously mentioned, this is caused by a arterial blockage by enlarging plaque formation which occludes the lumen, or plaque rupture which causes clot formation which occludes blood flow. If ...
Is dietary deficiency of calcium a factor in rickets? Use of current evidence for our understanding of the disease in the pastS. Mays a b cM.B. Brickley d
(HAE), an autosomal-dominant disease caused by C1-INH deficiency due to a mutation in the C1-inhibitor gene [165,166]. Studies have been done to evaluate whether CI-INH may protect from lung injury in vivo possibly explaining the underlying mechanisms mediating protection. These studies ...
The underlying pathological processes of CAVD involve dysfunction of VECs chronic inflammation, lipid deposition, remodeling of the extracellular matrix, and ectopic calcification primarily caused by VICs osteodifferentiation (Kraler et al. 2022; Moncla et al. 2023). Healthy VECs maintain an endothelial...
Glycogen storage diseases (GSDs) are a group of rare genetic disorders caused by deficiency of an enzyme involved in glycogen production, degradation, or glucose breakdown, primarily affecting the liver, skeletal muscle, or both (Marion and Paljevic, 2020; Ozen, 2007). Patients with GSDs...
Interestingly, the complexity of ATP1A3-related disorders is emphasized by the fact that clinically distinct neurological diseases seem to be caused by mutations in a single gene. In fact, amino acid substitutions in the same position have been shown to cause RDP or AHC. One example of this ...
It has been suggested that thrombosis of the stenosed vessel, which entails the acute onset of the clinical syndrome, may also be a consequence of a state of hypercoagulability, which may be caused by deficiency of protein C or S or even lupus anticoagulant.23, 24 Thrombosis may be also ...