Plant disease, an impairment of the normal state of a plant that interrrupts or modifies its vital functions. Plant diseases can be classified as infectious or noninfectious, depending on the causative agent. Learn more about the importance, transmission
Myelination is often compromised in ATR-X intellectual disability syndrome patients. Here, the authors show that the causative gene, ATRX, can regulate myelination in mice by modulating systemic thyroxine levels and by supporting oligodendrocyte progenitor differentiation. ...
Several sight-threatening ocular pathologies, including infectious keratitis, orbital cellulitis and endophthalmitis are caused by a wide variety of different pathogens, including bacteria, fungi, protists and viruses; co-infection is also possible. Many of the causative pathogens are universal, whereas o...
Sickle cell disease (SCD) is a group of genetic disorders in which an abnormal hemoglobin molecule (hemoglobin S) transforms red blood cells into a “sickle-shaped” cell.
the incidence of these infections falls in adulthood and later life. The frequency ofcommon coldsis explained on the grounds that a host of different viral agents all induce similar respiratory infections, and, while a single attack confers immunity against the specific causative agent, it provides...
1.1. Early onset Alzheimer's disease causative genes (APP, PSEN1, and PSEN2) The amyloid precursor protein gene (APP, OMIM 104,760, chromosome 21q21) encodes a ubiquitously expressed, integral Type I membrane glycoprotein that exists as different alternatively spliced isoforms, with three predominant...
Cultures for causative organisms for PIDAdditional STI tests: HIV , syphilis Pregnancy test (to rule out ectopic pregnancy )Imaging:Transvaginal ultrasound if clinical and laboratory findings inconclusive or complications suspected May show thickened fallopian tube , free pelvic fluid, or indistinct ...
Chagas diseaseis a major cause of cardiac disease in Latin America and is being recognized in North America as well, owing to increasing emigration from endemic areas.49The causative organism isTrypanosoma cruzi,which is spread by an insect vector. Chronic heart disease develops in 10% to 40% ...
actinomycetemcomitans), another causative agent of PD, induces ACPA and may be a trigger of RA [49]. EBV-citrullinated peptides arise from EBNA-1 [42] and EBNA-2 [43]. Antibodies against the viral specific citrullinated peptides appear to be cross-reactive with ACPAs targeting the ...
In summary, our results suggest that disease genes in the DL fraction correlated with earlier age of onset, multiple affected systems and AD disorders (Supplementary Table6). Given this, we compared the genes in our FUSIL bins with the genes identified as likely to be causative of developmental...