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We found that ESC-derived ExMVs enhanced cell survival, improved the expansion rate, and upregulated the expression of early pluripotent stem cell markers (Oct-4, Nanog, and Rex-1) and early hematopoietic stem cell markers (Scl, HoxB4, and GATA 2) in these cells [23]. Following this ...
Traditional drug discovery approach is based on one drug-one target, that is associated with very lengthy timelines, high costs and very low success rates.
Ge W, Davis ME, Hines HC, Irvin KM, Simmen RC: Association of a genetic marker with blood serum insulin-like growth factor-I concentration and growth traits in Angus cattle. J Anim Sci. 2001, 79 (7): 1757-1762. CAS PubMed Google Scholar Ge W, Davis ME, Hines HC, Irvin KM, Si...
Dhayalan A, Kudithipudi S, Rathert P, Jeltsch A . Specificity analysis-based identification of new methylation targets of the SET7/9 protein lysine methyltransferase. Chem Biol 2011; 18: 111–120. Article CAS Google Scholar Couture JF, Collazo E, Hauk G, Trievel RC . Structural basis fo...
Plant gametophytes play central roles in sexual reproduction. A hallmark of the plant life cycle is that gene expression is required in the haploid gametophytes. Consequently, many mutant phenotypes are expressed in this phase. We perform a quantitative
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