Correction to: Discovery of the RANKL/RANK/OPG systemdoi:10.1007/s00774-021-01203-8OSTEOPOROSISOSTEOCLASTOGENESISIn the original publication of the article, reference 12 was published incorrectly as follows.Yasuda, HisatakaJournal of Bone & Mineral Metabolism...
Role of DNA methylation in the regulation of the RANKL-OPG system in human bone. Epigenetics 2012; 7: 83–91. Article CAS Google Scholar Milutinovic S, D'Alessio AC, Detich N, Szyf M . Valproate induces widespread epigenetic reprogramming which involves demethylation of specific genes. ...
Breast cancer (BC) is the most prevalent cancer and the leading cause of death among women worldwide. The osteoprotegerin (OPG) cytokine, a decoy receptor for RANKL and a key player in bone homeostasis, has pro-and anti-carcinogenic effects in various ty
The discovery of fibroblast growth factor 23 (FGF23), a novel bone-derived hormone that inhibits phosphate reabsorption and calcitriol production by the ki... J Stubbs,S Liu,LD Quarles - 《Semin Dial》 被引量: 165发表: 2010年 OPG/RANK/RANKL signaling system and its significance in nephrology...
Integrins have been the research focus of cell-extracellular matrix adhesion (ECM) and cytokine receptor signal transduction. They are involved in the regulation of bone metabolism of bone precursor cells, mesenchymal stem cells (MSCs), osteoblasts (OBs)
RANKL have the ability to bind to C-FMS and RANK receptors (respectively) on osteoclast progenitors, triggering subsequent signals that promote osteoclast differentiation by activating the transcription factor nuclear factor of activated T cells 1 (NFATc1)5. Osteoblasts secrete osteoprotegerin (OPG) and...
Martin TJ.Historically significant events in the discovery of RANK/RANKL/OPG.World J Orthop.2013.186-197Martin T J.Historically significant events in the discovery of RANK/ RANKL/OPG[J].World J Orthop, 2013, 4 ( 4 ) : 186.Martin, T.J. Historically significant events in the discovery of ...
RANKL have the ability to bind to C-FMS and RANK receptors (respectively) on osteoclast progenitors, triggering subsequent signals that promote osteoclast differentiation by activating the transcription factor nuclear factor of activated T cells 1 (NFATc1)5. Osteoblasts secrete osteoprotegerin (OPG) and...