Hepatitis C VirusisolationAfter nearly 6 years of intensive investigations between 1982 and 1988 in my laboratory at Chiron corporation, in which numerous molecular biological methods were used to investigate the viral aetiology of parenterally transmitted non-A, non-B viral hepatitis (NANBH), a ...
根据文章第一段“Threescientists who played central roles in thediscovery of the hepatitis C virus have beenawarded the Nobel Prize in Physiology orMedicine 2020”可知,故选C项。29.A细节理解题。根据文章第二段“Inthe 1980s, Houghton managed to isolatethe genetic sequence of the virus”可知Houghton...
The Nobel Prize for Physiology or Medicine, in the year 2020, has been awarded to three scientists, Harvey Alter, Michael Houghton, and Charles Rice, for jointly discovering the hepatitis C virus (HCV). This remarkable achievement is a huge breakthrough in the fight against hepatitis C. Most...
“Serum hepatitis” can be caused by a DNA virus of the Hepadna family (hepatitis B virus, HBV), with or without an associated RNA virus of the Deltaviridae family (Hepatitis D virus, HDV), or an RNA virus of the Flaviviridae family (Hepatitis C virus, HCV) (Figure 1). This form o...
Discovery of new Hepatitis C virus mechanism by Osaka University SPP inhibition reduces production of infectious HCV particles and pathogenesis, Credit: Aizawa and Okamato et al. Nat Commun (2016) Researchers at Osaka University, Japan uncovered the mechanisms that suppress the propagation of the ...
Twenty-five years ago CDC played a pivotal role in the discovery of the virus that causes hepatitis C. After the isolation of HCV, implementation of screening of blood products and organs for donation led to a decrease in rates of HCV infection between 1990 and 2009. In spite of these ...
Researchers at Osaka University, Japan uncovered the mechanisms that suppress the propagation of the hepatitis C virus (HCV) with the potential of improving pathological liver conditions. Using model mice, they confirmed that when a certain enzyme is inhibited, HCV particle production is reduced leadin...
Discovery of Beclabuvir: A Potent Allosteric Inhibitor of the Hepatitis C Virus PolymeraseDiscovery of Beclabuvir: A Potent Allosteric Inhibitor of the Hepatitis C Virus PolymeraseAsunaprevirBeclabuvirDaclatasvirHCVHepatitis C virusNS5B inhibitorPolymerase...
In the 15 years since the discovery of hepatitis C virus (HCV), much has been learned about its role as a major causative agent of human liver disease and ... P Simmonds - 《Journal of General Virology》 被引量: 1781发表: 2004年 Hepatitis C virus: The major causative agent of viral ...
Hepatitis C virus (HCV), identified approximately 25 years ago, is recognised as the cause of several clinical conditions besides chronic hepatitis. New compounds with direct antiviral activity have recently been introduced. These drugs promise to outdo old therapies based on interferon and ribavirin ...