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糖基化蛋白质组学筛选发现ST6GAL1的底物糖蛋白PODXL是对抗CTC簇化疗逃逸与转移的候选靶点。 【文章标题】Dynamic Glycoprotein Hyposialylation Promotes Chemotherapy Evasion and Metastatic Seeding of Quiescent Circulating Tumor Cell Clusters in Breast Cancer 【发表期刊】Cancer Discovery 【影响因子】29.497 【发表时间...
2024年5月10日晚,BioArt编辑部邀请了Cancer Discovery的执行主编Elizabeth S. McKenna博士,中国医学科学院肿瘤医院刘芝华研究员、复旦大学生物医学研究院/附属肿瘤医院柳素玲教授、四川大学华西第二医院周圣涛教授、四川大学汪源研究员、北京大学系统生物医学研究所冯嘉汶研究员,成功举办了首期“BioArt期刊编辑访谈”(BioArt期刊...
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The Skullcap genus has been used for centuries in TCM for treatment of different medical conditions. Clinical work has shown that preparations based on Scutellaria barbata during chemotherapy can reduce the risk of metastatic tumors. CEPAMS Group Leader based at Shanghai Dr Evangelos Tatsis...
Recent discovery of the cancer cell plasticity and heterogeneity makes the CSC population a moving target that could be hard to track and eradicate. Understanding the signaling mechanisms regulating CSCs during the course of cancer treatment can be indispensable for the optimization of current treatment...
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Over the past 20 years, coronaviruses have caused a large number of deaths. It started in 2002-2003, with the Severe Acute Respiratory Syndrome (SARS, caused by SARS-CoV) which shed light on the potential threat of this class of viruses associated with c