DNA methylation is a quintessential epigenetic mechanism. Widely considered a stable regulator of gene silencing, it represents a form of “molecular braille,” chemically printed on DNA to regulate its structure and the expression of genetic information. However, there was a time when methyl groups...
Discovering the structure of DNA DNA = Deoxyribose nucleic acid Made out of sugars (deoxyribose), phosphates and nitrogen bases Discovering the structure of DNA Structure was discovered in 1953 by James Watson and Francis Crick And I got to hang out with Watson!!! Discovering the structure of D...
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(iii) We quantitatively assessed positional distributions and LD structure of the mtDNA variants by parallelly comparing with those of nDNA. (iv) We performed genome-wide scans to investigate the mtDNA–nDNA and mtCN–nDNA genotype associations. (v) Finally, we conducted mitochondrial genomewide ...
and periodisation (how often?). Some philosophers of science have argued for continuity, others have sought multiple revolutions: the Darwinian revolution, the Quantum revolution, the DNA revolution, and so on, while others claim that the real Scientific Revolution came in the 19th century when ...
Notably, one homolog, EphcCasλ, is experimentally validated for self-processing pre-crRNA, DNA cleavage, and trans-cleavage, showing promise for CRISPR-based pathogen detection. This study highlights an innovative approach for discovering CRISPR-Cas systems with specific functions, emphasizing their ...
The local culture of the corporation has many sources: the vision of the founder, ideas introduced through mergers and acquisitions, cataclysmic events in the history of the corporation (public ones like the depression of the 1920s, and private ones like the time the CFO decamped with the corp...
Moreover, in this breed, we see several genes related to DNA repair and oxidative stress that are also related to solar radiation. In Nubian breed, the GO results showed links with energetic metabolism, protein, and fatty acids synthesis regulation, but also catabolic processes (proteins and ...
Small molecule drugs form the backbone of modern medicine’s therapeutic arsenal. Often less appreciated is the role that small molecules have had in advancing basic biology. In this Review, we highlight how resistance mutations have unlocked the potenti
A FASTA file with the deep sequencing reads and the adapter sequence (both in RNA or DNA alphabet). Output A FASTA file with the clipped reads. FASTA IDs are retained. If no matches to the adapter prefixes are identified in a given read, the unclipped read is output. ...