The narrow diameter of the peripheral airways means that particles can more easily collide with the surface and cause damage compared to the larger airways [2]. The small airways have been defined as < 2 mm diameter and arise from the 4th – 13th generation of airway branching (taking ...
Cardiovascular disease (CVD) remains the predominant cause of mortality and disability worldwide. Against this backdrop, finding effective drugs for the pharmacological treatment of CVD has become one of the most urgent and challenging issues in medical
and Adrenal Gland” (SBLA) syndrome, is a rare autosomal dominant cancer predisposition syndrome [1]. First described over fifty years ago, the initial suspicion was raised by Frederick P. Li and Joseph F. Fraumeni as an “increased familial susceptibility to cancer” was observed “not only b...
Recent research indicated that Toll-like receptor 4 (TLR4) and the nuclear factor kappa B (NF-κB) signalling pathway play a role in promoting the activation of cytokines such as TNF-α, IL-6, and IL-1β to exacerbate inflammation, leading to subsequent myocardial tissue damage [18]. Inhib...
Keywords: immunotherapy,cancer vaccine,heterogeneity,tumor microenvironment,neoantigen,precision medicine Cite this article: Shen Y, Yu L, Xu X, et al.Neoantigen vaccine and neoantigen‐specific cell adoptive transfer therapy in solid tumors: Challenges and future directions.Cancer Innovation,2022, 1(2)...
Purpose:Heavy metals pose a significant environmental threat due to their widespread occurrence and harmful effects on ecosystems and human health. This st
[36,47,48]. Cardiac toxicity, characterized by QT interval prolongation, T-wave flattening, ST segment depression, and arrhythmias, has been reported with specific HDAC inhibitors and underscores the importance of cardiac monitoring during therapy [43,49]. In addition, some studies have suggested ...
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Section 4 discusses the renewable energy option. Section 5 concludes the paper. 2. Modelling the Power Consumption of Cellular BSs To understand the power consumption problems in cellular BSs, one must explore the architecture of these systems and the power consumption of their parts. BSs act as...
Deep- fakes can also be employed as tools for political manipulation, influence elections, and destabilize public trust in political institutions [3,4]. In addition, this technology enables malicious actors to create and distribute non-consensual explicit content to harass and cause reputational ...