Antibody-drug conjugates (ADCs) aim to take advantage of the specificity of monoclonal antibodies (mAbs) to deliver potent cytotoxic drugs selectively to antigen-expressing tumor cells. Despite the simple concept, various parameters must be considered when designing optimal ADCs, such as selection of ...
Advances in the treatment of pediatric relapsed leukemia have not mirrored the successes of upfront therapy, and newer treatments are desperately needed in order to improve survival in these challenging patients. Recent improvements in our knowledge of cancer biology have revealed an extensive number ...
USA The evidence to date, coupled with advances in immunology and genetics has afforded the field an unparalleled opportunity to investigate the hypothesis that a subset of patients with schizophrenia may manifest an immunophenotype, toward new potential diagnostics and therapeutics to reduce risk, allevi...
In this paper, the trends and interactions among these components are identified and reviewed in relation to the technology developments. The review then concludes by exploring some of the opportunities and directions. Keywords: web mapping; Web GIS; Internet; online; web services; digital earth; ...
5G technology will contain a range of networks to fulfill typical requirements of end-users such as voice, video, and data, along with the additional capabilities of seeming less connectivity across devices, machines, vehicles, sensors, and so on [5,6]. However, achieving the full potential ...
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* Correspondence: muhammad.a.khan@cranfield.ac.uk Citation: Olisa, S.C.; Khan, M.A.; Starr, A. Review of Current Guided Wave Ultrasonic Testing (GWUT) Limitations and Future Directions. Sensors 2021, 21, 811. https://doi.org/ 10.3390/s21030811 Academic Editor: Klaus Stefan Drese ...
With the north-south oriented (Bay head to mouth) Chesapeake Bay main channel, different wind directions cause different degrees of destratification and associated reduction in hypoxia [6–10]. Hypoxia describes a condition of depressed dissolved oxygen, defined as concentrations less than 2 mg/L [...
algorithms Review From Intrusion Detection to an Intrusion Response System: Fundamentals, Requirements, and Future Directions Shahid Anwar 1,*, Jasni Mohamad Zain 2, Mohamad Fadli Zolkipli 1, Zakira Inayat 3,4, Suleman Khan 4, Bokolo Anthony 1 and Victor Chang 5 1 Faculty of Computer Systems ...
In Section 3, we summarize the performance of the published examples of transparent antennas, referring to the figure of merit (FoM) of the TCFs. Finally, the role and promising contribution of the transparent antenna that can be directly integrated within active displays and denoted as Antenna-...