(SVV-001) was first tested intravenously in a five-log increment dose escalation phase I study in patients with nueroendocrine cancers, 6 small cell and 24 carcinoid- type, and was found to be well tolerated and showed evidence of intratumoral viral replication in delayed kinetics in the ...
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6 to achieve two key goals: first an attempt to minimise long-term steroid side effects and reduce steroid use by aiming to taper this to o10 mg of prednisolone a day; and second, as will be discussed further in the section below, to introduce a more targeted approach to immunomodulation...
Healthcare Industry 4.0 refers to intelligent operation processes in the medical industry. With the development of information technology, large-scale grou
Ligmann-Zielinska, ArikaBone, ChrisJournal of Land Use ScienceO'Sullivan, D., Evans, T., Manson, S., Metcalf, S., Ligmann-Zielinska, A. and Bone, C.: 649 Strategic directions for agent-based modeling: avoiding the YAAWN syndrome, J. Land Use 650 Sci., 11(2), 177-187, doi:...
While most FGR infants are born preterm, the adverse respiratory outcomes such as BPD attributable to the FGR state, are independent of the degree of prematurity, indicating possible alignment of pathophysiology between FGR and BPD [10], [11]. In a large multi-centric study on >1200 infants ...
includes a variety of motifs on the surface or near the surface in depressions or canyons of SVV-001 that may bind to specific integrins that are present on tumor cells (eg, α1β4 on small-cell lung carcinoma [SCLC]).2 Liu et al identified α2,3- and α2,6-linked sialic acids as...
includes a variety of motifs on the surface or near the surface in depressions or canyons of SVV-001 that may bind to specific integrins that are present on tumor cells (eg, α1β4 on small-cell lung carcinoma [SCLC]).2 Liu et al identified α2,3- and α2,6-linked sialic acids as...
Papayannopoulos IA (1995) The interpretation of collision-induced dissociation tandem mass-spectra of peptides. Mass Spectrom Rev 14(1):49–73. doi:10.1002/mas.1280140104 Article CAS Google Scholar Hardman M, Makarov AA (2003) Interfacing the orbitrap mass analyzer to an electrospray ion sourc...
However, extant obesity treatments have largely failed to meet the needs of Black and Latino adults [11, 12]. Indeed, novel and effective interventions to promote equitable treatment access and benefit are urgently needed for Black and Latino adults. In this review, we seek to inform future ...