CAR T-cell therapy leverages engineered T-cells to target specific antigens on tumor cells, leading to their elimination. Current approved therapies target B-cell maturation antigen (BCMA); new targets are under investigation, such as G-protein-coupled receptor class C group 5 member D (GPRC5D...
For most cancer patients, PD-1/PD-L1 pathway is not the sole speed-limiting factor of antitumor immunity, and it is insufficient to motivate effective antitumor immune response by blocking PD-1/PD-L1 axis. It has been validated that some combination therapies, including α-PD-1/PD-L1 plus...
“Narus and Whitecross Join Forces to Deliver Comprehensive Usage Pattern Analysis Applications for IP Service Providers,” Press Release, Palo Alto, CA, Mar. 27, 2000, 4 pages. “Enterprise Application Servers,” Powerstation Technologies, Inc., undated, 4 pages. “P6000 Fault-Tolerant Multi...
most likely due to better treatment of myocardial infarction [66]. The incidence of HFpEF also decreased, with similar overall rate changes for women and men over 10 years (− 27%; − 2.7% per year), probably due to better treatment of comorbidities [69]. However...
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Another area that mushroomed subsequent to the pre-computer era is instrumentation. New instruments which were more accurate and sophisticated were developed for measuring all kinds of hydrologic variables, such as velocity, soil moisture, water and air quality parameters, fluxes in porous media, energ...
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Particularly, most robots' resilience is restricted due to slow technological developments in the areas of hardware prototypes, actuators, and communications, and thus the system may not recover its original function even if it suffers slight failures. Considering the number of robots described in the...