DNA loop extrusion is asymmetric but can switch directiondoi:10.1038/s41588-025-02102-8Chiara AnaniaNature Publishing Group USNature Genetics
Which direction is the template DNA read by the RNA polymerase? The structure of DNA is a double helix, meaning it is made up of two strands. What is the orientation of these strands? What determines the direction of replication of DNA?
They found that certain DNA-patterns, which affect how genes are __32_, are different between IVF and non-IVF children . There’s no way to tell if that’s because of the __33_used to produce the IVF babies or whether the difference has something to do with the underlying infertility...
What direction does DNA replication read? How does the machinery work? What are key proteins?Directionality of DNA molecules:The DNA strand molecules have a directionality. The strands are described as running anti-parallel to each other. One strand runs from 5' to 3' while...
These NPs combine the enzymatic activity of DNase with the inhibitory properties of STING antagonists to reduce the accumulation of immunogenic DNA fragments and alleviate the chronic inflammatory cascade. DNase-loaded NPs provide a synergistic approach to ameliorating neuroinflammation and promoting tissue ...
These kinds of phenomena are not found often in nature. There are very few materials known that behave in the wrong way. Another well-known example is the Rochelle salt, where charges build up and form an ordered pattern at a higher temperature, where at a lower temperature the...
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The 9-1-1 DNA checkpoint clamp is loaded onto 5′-recessed DNA to activate the DNA damage checkpoint that arrests the cell cycle. The 9-1-1 clamp is a heterotrimeric ring that is loaded in Saccharomyces cerevisiae by Rad24-RFC (hRAD17-RFC), an alternate clamp loader in which Rad24 rep...
Burbano, a geneticist who works on evolutionary genomics and ancient DNA. The article focuses on one of the latest research topics of Hernán: how our DNA is connected to corn plants.ALMA is the digital platform of "Obra Social La Caixa". They’ve created a social network to show their ...
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