Dipyrone, also known as metamizol, and tramadol are drugs that are widely used for the treatment of pain; however, side effects can limit their use. As dipyrone and tramadol produce side effects that are dose dependent, it seems appropriate to combine these drugs to reduce their dose ...
Gastric side effects represent the most common adverse drug effects of the widely used nonsteroidal anti-inflammatory drugs. The gastric effects of these drugs may be comparable in experimental ulcer models. In the present study, the gastric ulcerogenic activity of nabumetone and dipyrone were ...
No side-effects were reported.doi:10.1185/03007998009109498Muklierjee, SSood, SudhaTaylor & FrancisCurrent Medical Research & OpinionMukherjee S, Sood S (1980) A controlled evaluation of orally administered aspirin, dipyrone and placebo in patients with post-operative pain. Curr Med Res 6: 619–...
moreover, alternative analgesic and antipyretic agents are not devoid of serious side effects. conclusions: it is therefore necessary to establish the incidence of agranulocytosis in latin america and the role of dipyrone. the ongoing latin study is a multicenter international case-control study that...
Although dipyrone effects on renal vasodilator prostaglandin synthesis are documented, little is known about its potential renal side effects, especially in the critical care environment.doi:10.1097/EJA.0000000000000627Stueber, ThomasBuessecker, Laura
Dipyrone (metamizol), a non-opioid analgesic, is widely used for acute and chronic pain management. Although not marketed in all countries because of concerns of possible side effects like agranulocytosis, this potent analgesic is frequently used worldwide.A severe anaphylactic reaction without any ...
side effectsA randomized, double-blind, multicentre clinical trial was designed to compared the analgesic efficacy of i.m. dipyrone 1 and 2 g, i.m. diclofenac sodium and i.m. pethidine in acute renal colic. The study was carried out in 451 patients in 13 Spanish hospitals. Ureteric colic...
Drug-related side effects and adverse reactionsDrug hypersensitivityThe safety of dipyrone has been the object of numerous debates, since severe allergic reactions to it can occur with an estimated incidence of 1 in 5000 parenteral administrations. We report the case of one patient who, after an ...
Side effects and vital parameters were also recorded. After the 24 h study period, a significant pain relief was observed in all three groups. The consumption of morphine via PCA, however, was significantly lower in group 2 (tramadol/dipyrone) than in the tramadol or the placebo group, and ...
No side-effects were reported.doi:10.1185/03007998009109499C V PatelM G KoppikarM S PatelG B ParulkarTaylor & FrancisCurrent Medical Research and OpinionPatel CV, Koppikar MG, Patel MS, Parulkar GB. A double-blind comparison of parenteral dipyrone and pethidine in the treatment of post-operative...