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Experiments with oral ingestion of the compound could be described by the use of a corresponding pharmacokinetic model with two consecutive first order input steps, representing the dissolution and absorption processes. The disposition rate constants (beta) were within the range of 0.0051--0.0083 min....
VP-16 (etoposide) has been currently used for the treatment of malignant gliomas not only as a chemotherapeutic agent for induction of initial remission but also as a drug for the long-term treatment after remission of the tumors. When VP-16 is used for the latter purpose, however, two maj...
BUY DIPYRIDAMOLE ONLINE USA Dipyridamole is an immunomodulating drug that improves microcirculation Pharmacological properties. Pharmacodynamics. Expands coronary vessels (mainly arterioles) and causes a significant increase in the volume flow rate. Increases the oxygen content in the venous blood of the coro...
A second-order rate constant k(Dipyridamole+OH·) of 72±0.11×1010M?1 s?1 and of 54±0.15×1010 M?1 s?1 was measured by Fenton chemistry and by radiation chemistry, respectively. Mannitol was used as an internal standard for hydroxyl radicals in steady-state competition experiments with ...
v.f.patel.et al. self correcting monolithic floating matrix tablet of dipyridamol tablet of dipyridamol : influence of formulation variable.ijpsonline .com ip 59,90.142.112 page 219-225
The fluorescence quenching of serum albumin at three different temperatures revealed that the mechanism involved is static and the binding constant of the interaction was found to be of the order of 10 M. The reaction was found to be spontaneous and involved hydrophobic interactions. Synchronous, ...
The final concentration of each drug was of the same order of magnitude as during clinical treatment. The leucocyte migration under agarose was significantly increased by DIPY at a concentration of 100 μg/ml. The release/production of LMIA was inhibited by DIPY at 1 μg/ml and by LASA at...
It is often recommended that acetylsalicylic acid (ASA) and dipyridamole should be given together in order to obtain secondary prophylaxis against certain ischaemic diseases. Therefore, the possible pharmacokinetic interactions between these agents were assessed following single-dose exposures in 14 healthy ...
dipyridamole inhibited endothelial cell-mediated LDL oxidation, their degradation by monocytes, and cytotoxicity.5In comparison with ascorbic acid, -tocopherol and probucol, dipyridamole was the more efficient antioxidant with the following order of activity: dipyridamole > probucol > ascorbic acid > -...