In 1976 at Seveso, Italy, a chemical plant explosion occurred, marked in the history as “Seveso disaster”. The accident caused the spreading of over 30 kg of TCDD and other chemicals about 18 square kilometers, which was the highest ever-recorded residential human exposure t...
Accidental release of 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) at Seveso, Italy. II TCDD distribution in the soil surface layer Ecotoxicol Environ Saf. 1980;4(3):298-320.DiDomenico, A., Silano, V., Viviano, G., and Zapponi, G. (1980). Accidental release of 2,3,7,8- ...
Aylward LL et al (2004) Concentration-dependent TCDD elimination kinetics in humans: toxicokinetic modeling for moderately to highly exposed adults from Seveso, Italy, and Vienna, Austria, and impact on dose estimates for the NIOSH cohort. J Expo Sci Environ Epidemiol 15:51–65 Google Scholar Ayl...
The Seveso, Italy accident in 1976 caused the contamination of a large population by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Possible long-term effects have been examined through mortality and cancer incidence studies. We have updated the cancer incidence study which now covers the period 19...
volcanic eruptions and forest fires. Waste incineration, particularly if combustion is incomplete, is among the largest contributors to the release of PCDDs and PCDFs into the environment. Due to their persistence, PCDDs, PCDFs and PCBs are part of the so-called persistent organic pollutants ...
Section > Chapter Behnisch, P.A.; Hosoe, K.; Sakai, S. Environment International 27(6): 495-519 2001 ISSN/ISBN:0160-4120 11800431 10.1016/s0160-4120(01)00029-0 045567601 Full-Text Article emailed within 0-6 h Buy Now for$19.90 ...
In 1976, an explosion at a trichlorophenol plant near Seveso, Italy, resulted in the highest TCDD exposure known in human residential populations (=-=Mocarelli et al. 1988-=-; Needham et al. 1991). To date, few studies of the reproductive health effects of TCDD exposure in Seveso have ...
We have previously shown that high serum concentrations of TCDD in parents from Seveso, Italy, were linked to their having a relative increase in the number of female births after the parents exposure to a release of dioxin in 1976. We have continued the study to determine whether the parents...
No transgenerational studies are available in humans, but some evidence of the effects produced by the dioxin exposure of pregnant women on F2 generation might be derived by the population studies after the Seveso incident. On July 10, 1976, a chemical plant explosion in Seveso, Italy, deposited...
Another great disaster that has grabbed the world's attention is the Seveso incident in 1976, where an explosion in an industrial plant exposed the population of Seveso, Italy, to a substantial amount of pure 2,3,7,8-tetrachloro-p-dioxin, with chloracne and some types of cancer as the ...