The neonicotinoids have low toxicity to mammals, birds, and fish (Tomizawa and Casida, 2003, 2005). As of 2010, there were no records of cross-resistance of insect nAChR agonists with other ectoparasiticides (such as carbamates, organophosphates, or pyrethroids) (Vo et al, 2010). ...
Toxicity evaluation LD50 acute, rats, oral 2450 mg/kg D50 acute, rabbits, dermal >2000 mg/kg As a general rule, dogs and cats tolerate dinotefuran quite well. Dinotefuran is slightly irritant to the eyes and the skin. Dinotefuran is not carcinogenic, teratogenic or mutagenic. ...
Seizures secondary to hypoxia may occur. Rhabdomyolysis was not reported in toxicity studies in animals but has occurred in humans with indoxacarb poisoning.31 Acute renal failure has also been reported in humans, and in most cases was considered to be secondary to hemoglobinemia or myoglobinemia....
Dinotefuran formulations include the technical product, formulation intermediates, soluble concentrates, granulars, soluble granules, baits, gels, and ready-to-use (RTU) spraysEXP 316 4.6 Toxicity LD50 in male, female mice, male, female rats (mg/kg): 2450, 2275, 2804, 2000 orally; in rats (...
NIT is a frequently used pesticide due to its good solubility in water and ease of application and it remains stable in nature for a long time. For these reasons, although it has a lower affinity in mammals, it causes toxicity in humans and animals over time due to long-term exposure ...