Peak digoxin body stores of 8 to 12 mcg/kg generally provide a therapeutic effect with minimum risk of toxicity in most patients with heart failure and normal sinus rhythm. The loading dose should be administered in several fractions, with approximately half the total given as the first dose. ...
Almost any type of arrhythmia has been reported with digoxin toxicity; however, classical examples include atrial tachycardia with advanced AV block and accelerated junctional rhythms, in addition to bidirectional ventricular tachycardias. Treatment of toxicity usually involves stopping the medication in ...
Since the elderly appear to be at high risk for digoxin toxicity, the inappropriate use of this medication to treat these conditions could result in significant and unnecessary morbidity. It is proposed that echocardiography should be performed in most elderly patients when congestive heart failure is...
CONTEXT: Digoxin is used in the treatment of patients with cardiac dysfunction, though toxicity sometimes results from the use of this medication. In 1986, the US Food and Drug Administration (FDA) approved a digoxin immune Fab for the treatment of such patients. In 2001, the FDA approved a...
This compound is widely used in the treatment of various heart conditions, namely atrial fibrillation, atrial flutter, and sometimes heart failure that cannot be controlled by other medication [45]. Despite its wide therapeutic use, compound 2 has a low therapeutic index and toxicity is common. ...
In this lesson, we will learn about digoxin, a medication that helps treat certain heart problems. Find out the common side effects that can occur when receiving this medication. What is Digoxin? The heart can be an imperfect organ. Though it can't literally 'break in two' as pop songs...
A decrease in 30 Hz-flicker ERG signal amplitude is the accepted visual electrophysiological diagnostic of digoxin toxicity. Digoxin toxicity is treated by stopping the medication. Recovery from digoxin toxicity is assessed by monitoring of symptoms. 展开 ...
(Pharmacology) a glycoside extracted from the leaves of the woolly foxglove (Digitalis lanata) and used in the treatment of heart failure. Formula: C41H64O14 Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006...
Cardiovascular disease is ubiquitous within the elderly population and requires treatment with multiple types of medications. As with any cardiovascular pharmaceutical regimen, the risk versus the benefit of each medication must be strongly considered. This is particularly true where, for various reasons,...
10.2 Treatment Chronic Overdose If there is suspicion of toxicity, discontinue Digoxin Tablets and place the patient on a cardiac monitor. Correct factors such as electrolyte abnormalities, thyroid dysfunction, and concomitant medications [see Dosage and Administration (2.5)]. Correct hypokalemia by adm...