Signs and symptoms Although allergic reactions to digoxin are rare, toxic reactions are not. The drug has a very low therapeutic index. Digoxin toxicity is a significant clinical problem and is one of the reasons the drug is not as commonly used today as in the past. Toxic signs are often...
Medical reports of the neonates who had serum digoxin concentrations >2 nanogram/milliliter (ng/ml) were reviewed in terms of patient demographics, serum digoxin concentrations, signs and symptoms of digoxin toxicity, serum digoxin and electrolyte levels, renal function ...
associated withdigoxin toxicity(Mulder et al., 1988) as have epileptic convulsions (Kerr et al., 1982). A manufacturing error resulted in intoxication in 179 patients; the majority of whom hadneurologic symptomsof vision problems,weakness, dizziness, and psychic complaints (Lely and van Enter, ...
Digoxin toxicityBackground: The striking similarities between signs and symptoms of digoxin intoxication and clinical picture of primary congestive heart failure (CHF) make their diagnosis relatively difficult. Narrow therapeutic window of digoxin and increasing mortality and morbidity due to its intoxication...
Misidentification of Digoxin Toxicity: Signs and symptoms of digoxin toxicity may be mistaken for worsening symptoms of congestive heart failure. (5.3) • Preserved Left Ventricular Systolic Function: Patients with heart failure with preserved left ventricular ejection fraction may be more susceptible to...
The results of this test can help identify any possible impairment in renal function and identify the presence of an infection (Vera, 2011). Risk 3 – Arrhythmias due to drug induced QT prolongation Educate Mr Buchanan on the signs and symptoms of arrhythmias such as: A fluttering in his ...
Use in conjunction with diuretics is a frequent cause of chronic toxicity.Failure to individualize dosage is another contributing factor.ManifestationsOverdosage is manifested by a wide variety of signs and symptoms that are difficult to distinguish from effects associated with cardiac disease (e.g., ...
It is likely that the excessive use of digoxin in elderly populations as discussed in this review is perhaps based on the prevalence of diastolic heart failure in the elderly as well as other co-morbid conditions that may mimic heart failure signs and symptoms. Since the elderly appear to be...
titrating to clinical effect. A proposed strategy has been toinfuse the initial or loading dose over 1 hour and then allow 1 hourafter the end of the infusion period to assess the need for additionaldoses. However, partial dosing has been associated with recurrences ofsymptoms in some digoxin...
Digoxin Toxicity.Having too much digoxin in your body may cause digoxin toxicity. Stop using digoxin and call your healthcare provider right away if you have any of the following symptoms of digoxin toxicity. If you are having these symptoms, your healthcare provider may run additional medical ...