The elimination half-life in the setting of renal failure has not been clearly defined. Patients with renal dysfunction have been successfully treated with DIGIBIND (digoxin immune fab) .4There is no evidence to suggest the time-course of therapeutic effect is any different in these patients than...
Define digoxin. digoxin synonyms, digoxin pronunciation, digoxin translation, English dictionary definition of digoxin. n. A cardiac glycoside, C41H64O14, obtained from the leaves of a foxglove, Digitalis lanata, with pharmacological effects similar to d
Digoxin Immune FabDigoxin immune Fab is a specific antidote that binds to digoxin (preventing and reversing pharmacologic and toxic effects and enhancing elimination) and can be used in the treatment of potentially life-threatening acute or chronic digoxin toxicity....
Digoxin immune Fab fragments (e.g. Digibind® from Glaxo SmithKline) are a promising treatment for life-threatening digoxin toxicosis. The Fab fragments are used as a specific antidote for digoxin since they inactivate the drug by directly binding to it. The fragments are produ...
It states that incidence of digoxin toxicity is l%-30% and Digoxin immune Fab reverses signs and symptoms of digoxin toxicity. It adds that Digoxin is an acceptable treatment to enhance signs and symptoms for heart failure for almost 2,000 years.Faye...
Digoxin immune fab is a safe and effective antidote, but cl... M Rahimi,A Mahdavinejad,S Shadnia,... - 《Heart Views the Official Journal of the Gulf Heart Association》 被引量: 0发表: 2021年 Impact of digoxin on all-cause mortality and re-hospitalizations in acute heart failure ...
the drug has a very narrow therapeutic index and can cause toxic side effects. The Fab fragment prepared from 26-10 that neutralises the activity of digoxin and can be used as an antidote in case of overdose of digitalis. Anti-digoxin monoclonal antibodies can also be used to measure serum...
Digoxin Toxicity and Use of DigoxinImmune Fab: Insights From a National Hospital DatabaseantidotedigoxinoutcomestoxicityThis study was developed to determine contemporary management of digoxin toxicity and clinical outcomes. Although the use of digoxin in heart failure management has declined, toxicity ...
Digoxin-specific Fab therapy: an effective antidote for digoxin toxicityDrugs & Therapy Perspectives -doi:10.2165/00042310-199506080-00005&NA;Springer International PublishingDrugs & Therapy PerspectivesDigoxin-specific Fab therapy: an effective antidote for digoxin toxicity. Drug Ther Perspect 1995 Oct 6;...
antidotearrhythmiaspoisonous planttoxicologyObjectiveTo describe a case in which digoxin-specific immune Fab was used successfully in a dog with severe oleander toxicosis secondary to ingesting plant material.Pao-Franco, AmarisHammond, Tara N.Weatherton, Linda K.DeClementi, CamilleForney, Scott D....