Digoxin Immune FabDigoxin immune Fab is a specific antidote that binds to digoxin (preventing and reversing pharmacologic and toxic effects and enhancing elimination) and can be used in the treatment of potentially life-threatening acute or chronic digoxin toxicity....
It is used as an antidote for overdose of digoxin. 结构式 药物别名 Digitalis antitoxin;Digoxin Immune Fab, Ovine;Digoxin-specific Antibody Fragments;Ovine digoxin immune fab 治疗类别 Antidotes;Digoxin Binding Activity;Immunoglobulin G;Immunoglobulins;Serum;Serum Globulins UNII号 YB12NQZ1YN ...
It states that incidence of digoxin toxicity is l%-30% and Digoxin immune Fab reverses signs and symptoms of digoxin toxicity. It adds that Digoxin is an acceptable treatment to enhance signs and symptoms for heart failure for almost 2,000 years.Faye Felicilda-Reynaldo, Rhea...
The Fab fragment prepared from 26-10 that neutralises the activity of digoxin and can be used as an antidote in case of overdose of digitalis. Anti-digoxin monoclonal antibodies can also be used to measure serum levels of the drug as a guide to therapy, and are useful in the investigation...
The wholesale price of the antidote, digoxin immune fab, has increased over 300% from 2010 to 2015. Our objective was to identify gaps in the existing literature with respect to the use of digoxin immune fab in cardioactive steroid toxicity in acute care settings. Methods : We used scoping ...
In severe digoxin toxicity, anantidigoxindrug designated digoxin immune Fab (Digibind) may be administered. Digoxin immune Fab consists of antigen-binding fragments derived from sheep antibodies to digoxin. Therapeutic Use of Digoxin The primary use fordigoxinis in the treatment ofCHF. The direct eff...
Digoxin-specific Fab therapy: an effective antidote for digoxin toxicityDrugs & Therapy Perspectives -doi:10.2165/00042310-199506080-00005&NA;Springer International PublishingDrugs & Therapy PerspectivesDigoxin-specific Fab therapy: an effective antidote for digoxin toxicity. Drug Ther Perspect 1995 Oct 6;...
Digoxin Toxicity and Use of DigoxinImmune Fab: Insights From a National Hospital Databasedoi:10.1016/j.jchf.2016.01.011antidotedigoxinoutcomestoxicityObjectives This study was developed to determine contemporary management of digoxin toxicity and clinical outcomes. Background Although the use of digoxin ...
antidotearrhythmiaspoisonous planttoxicologyObjectiveTo describe a case in which digoxin-specific immune Fab was used successfully in a dog with severe oleander toxicosis secondary to ingesting plant material.Pao-Franco, AmarisHammond, Tara N.Weatherton, Linda K.DeClementi, CamilleForney, Scott D....