A New Scale for the Assessment of Functional Status in Alzheimer's Disease and Related Disorders The need for direct assessment of functional status was addressed by developing a standardized operational procedure to examine areas of functional competence ... DA Loewenstein,A Ellen,D Ranjan,... -...
Concurrent administration of donepezil HCL and digoxin: assessment of pharmacokinetic changes. Br J Clin Pharmacol 1998;46(Suppl 1):40-4.Tiseo PJ,Perdomo CA,Friedhoff LT.Concurrent administration of donepezil HCI and digoxin: assessment of pharmacokinetic changes. British Journal of Clinical ...
Intravenous (IV): 8-12 mcg/kg (0.008-0.012 mg/kg) total loading dose; administer 50% initially; then may cautiously give 1/4 the loading dose every 6-8 hours twice; perform a careful assessment of clinical response and toxicity before each dose Oral: 10-15 mcg/kg total loading dose; ...
drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, which should be based on renal function, and it may be useful to monitor renal function [seeDOSAGE AND ADMINISTRATION]...
monitoring these patients for renal function and recurrent toxicity after DIF administration is essential. Assessment of renal function is performed by obtaining serum creatinine, glomerular filtration rate (GFR), and blood urea nitrogen (BUN) levels. Patients with renal failure require prolonged surveilla...
Concurrent administration of donepezil HCL and digoxin: assessment of pharmacokinetic changes. Br J Clin Pharmacol 1998;46(Suppl 1):40-4.Tiseo PJ, Perdomo CA, Friedhoff LT. Concurrent administration of donepezil HCl and digoxin: assessment of pharmacokinetic changes. Br J Clin Pharmacol 1998; 46...