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Fig.1a–c). To train and evaluate the model, we utilized WSIs and matched bulk RNA-seq gene expression data of sixteen cancer types available in The Cancer Genome Atlas (TCGA, Supplementary Table1): (1) bladder urothelial carcinoma (BLCA), (2) breast invasive ...
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Programmed cell death protein‐1 (PD-1)-targeted immunotherapy is approved for recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC) treatment. Although its efficacy correlates with PD-L1 expression, response is limited even among positive cases. We employed digital spatial profi...
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38 hypothetical clinical scenarios were created, seven of which pertained to BCC, 11 to squamous cell carcinoma (SCC), and 20 to malignant melanoma (MM; appendix p 2). Overall, the readability scores suggest that the t...
Influence of tumor mutational burden, inflammatory gene expression profile, and PD-L1 expression on response to pembrolizumab in head and neck squamous cell carcinoma. J Immunother Cancer. 2022;10(2):e003026. Article Google Scholar Batta N, Pandey M. Mutational spectrum of tobacco associated oral...
For use case 1, a dataset was generated from benign tissue regions of interest (ROI) of whole-slide images containing artifacts for both lung (WSI/patientn = 40, lung adenocarcinoman = 20/squamous cell carcinoman = 20; ROIn = 105) and colorectal (WSI/patientn = ...
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