Models that allowed a diffusion-limited exchange of helium between a perfusion-limited tissue compartment and an unperfused deep compartment provided better overall fit of the data and credible parameter estimates. Fit to the data was also improved by allowing countercurrent diffusion shunt of helium ...
This has been called perfusion rate–limited drug diffusion. If adequate drug concentrations can be achieved in plasma, it is unlikely that a barrier in the tissue will prevent drug diffusion to the site of infection as long as the tissue has an adequate blood supply. In critical care ...
Thus, oxygen delivery to tissues can become diffusion-limited during perfusion with stored blood, which has implications in scenarios, such as ex vivo organ perfusion, major hemorrhage, and pediatric transfusion. This trial was registered at www.clinicaltrials.gov as #ISRCTN13292277. Visual Abstract ...
as well astissue perfusion, this is often called theapparent diffusioncoefficient (ADC). The effects of perfusion can to some degree be compensated for by the choice of b-values[102]. Lastly, diffusion tensor imaging (DTI) measures the diffusion anisotropy and requires at least a set of 6 ...
et al. MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology 401–407, https://doi.org/10.1148/radiology.161.2.3763909. 3. Callaghan, P. T., Eccles, C. D. & Xia, Y. NMR microscopy of dynamic displacements: k-space and q-...
Although advanced MRI techniques like diffusion tensor imaging (DTI), perfusion MRI, MR spectroscopy (MRS), and susceptibility-weighted imaging (SWI) are incorporated into clinical MRI protocols, they still fall short6,7,8. The widely used multiparametric magnetic resonance imaging (mpMRI) approach ...
Use in combination with other imaging measures (e.g., T1, T2, magnetization transfer, perfusion, fast/slow diffusion, spectroscopy) may help to improve the specificity of DTI in complex diseases. In relatively homogeneous (single-fiber), well-characterized white matter tissues, the diffusion tensor...
Perfusion imaging Diffusion-weighted imaging Functional imaging Squamous cell carcinoma Recurrence 1. Introduction Head and neck imaging has been revolutionized during last 20 years. In squamous cell carcinoma (SCC), multislice computed tomography (CT) and new sequences in magnetic resonance (MR) imagin...
CeO2:Gd exhibited a high r1 value of 19.89 mM−1 s−1 due to the effective binding between the oxygen vacancies of the nanoparticles surface and water molecules, which accelerated the proton relaxation of the water molecules. They realized high-performance dynamic contrast-enhanced perfusion ...
[97]. They showed a significant association between the group with RAS mutation and the group without RAS mutation with MK [MK standard deviation (STD)], MD, and the perfusion fraction (FP). The best results were reached by MK STD with an area under curve (AUC) of 0.80, an accuracy ...