Schaefer IM, Fletcher CD: Malignant peripheral nerve sheath tumor (MPNST) arising in diffuse-type neurofibroma: clini- copathologic characterization in a series of 9 cases. Am J Surg Pathol 39:1234-1241, 2015Schaefer IM and Fletcher CD. Malignant pe- ripheral nerve sheath tumor (MPNST) ...
Twelve cases had family members with neurofibroma- tosis and malignancies. All cases were diagnosed with non-Hodgkin's lymphoma (NHL). The majority of cases were young with a mean age of 23 years (range 1.1 to 77 years; median 9.4 years) at lymphoma diag- nosis and two-t...
Neurofibroma, Retinoblastoma, Tuberous sclerosis, and some hereditary cancers with high penetrance expected at an early age are common in prenatal genetic diagnosis. Until now, PND has been reported in later onset and/or reduced penetrance inherited cancer predispositions, such as Familial adenomatous ...
Presentation of case: Authors present a case of a 55 year old patient with Type 1 neurofibromatosis (NF1) and a very large right thigh plexiform neurofibroma. The patient had increasing difficulty with mobilization due to this enlarging bulky mass. Preoperative embolization reduced the bleeding risk...
Massive soft tissue diffuse NeurofibromaElephantiasisNeurofibromaBackgound: Neurofibromas are well-known benign nerve sheath tumors that can assume several gross forms, among which massive soft tissue neurofibromas are the least common, and are restricted to patients with neurofibromatosis type 1 (NF1). ...
Postoperatively, histopathological examination showed features of diffuse neurofibroma. The present case report enables the surgeon to consider various rare differential diagnosis for swelling in the extremities, even when it is not reflected in the clinical or radiolo...
Background Neurofibromatosis type 1 (NF1) is an autosomal dominant condition with a high rate of new mutation and variable expression. Diffuse neurofibroma of the epidermis invading deeper organs is rare.We report a case of diffuse subcutaneous neurofibroma in the thoracoabdominal wall which had ...
The diffuse variant is a rare subtype of neurofibroma and is particularly rare in the larynx of an adult. Typically, neurofibromas present as painless, subcutaneous nodules in the context of neurofibromatosis type 1 (NF1), neurofibro-matosis type 2, or as sporadic neurofibromas. These neoplasms ...
Neurofibroma is a benign slow growing tumour of the peripheral nerve sheath; frequently associated with neurofibromatosis type I. Diffuse neurofibroma of maxillary sinus is an exceedingly rare tumour. We report a case of a 17-year-old male patient presented in the ENT department with a painless ...
The case to be described belongs to the latter category, and it presents some unusual localizations of neurofibromatous tumors. REPORT OF A CASE E. B., a man aged 21, for a number of years had multiple sessile tumors...