Intranasal diffuse large B-cell lymphoma of immunoblastic type with extensive osteolysis in a dogDogLymphomaIntranasalB-cellsImmunoblasticThis report describes a rare case of nasal lymphoma in a dog. A stray dog was presented with a swollen snout showing ulcerations and sanguinopurulent discharges....
CD40 ligand is necessary and sufficient to support primary diffuse large B-cell lymphoma cells in culture: a tool for in vitro preclinical studies with primary B-cell malignancies[J] . Daisuke Ito,Aric M. Frantz,Christina Williams,Rachael Thomas,Robert C. Burnett,Anne C. Avery,Matthew Breen,...
B-cell lymphomadogLymphomas are common in dogs and among them diffuse large B-cell lymphoma (DLBCL) represent ∼20%. The aim of this study was to evaluate and compare results of histopathological, immunohistochemical and fractal dimension (FD) analyses of canine DLBCL....
The dog died 59 months after initial presentation, and postmortem examination revealed generalized lymphadenopathy; the histopathological diagnosis was diffuse large B-cell lymphoma (DLBCL). Polymerase chain reaction for antigen receptor gene rearrangements revealed that the nMZL and DLBCL samples were ...
There is life in the old dog yet: thymidine kinase as predictive marker in diffuse large B-cell lymphoma.Thymidine kinase (TK) was initially described in the early 1950s as an enzyme being critically involved in the salvage pathway for DNA synthesis [1]. While the majority of TK activity ...
Diffuse large B-cell lymphomaDogLymphocyte-monocyte ratioPrognosisDiffuse large B-cell lymphoma (DLBCL) is the most frequent canine lymphoid neoplasm. Despite treatment, the majority of dogs with DLBCL experience tumour relapse and consequently die, so practical models to characterise dogs with a poor...
DogDLBCLT-cellsFlow cytometryChemo-immunotherapyPrognosisDogs with Diffuse Large B-Cell Lymphoma (DLBCL) benefit from the addition of active immunotherapy to traditional chemotherapy. We hypothesized that immune cells within neoplastic lymph nodes (LNs) may play a role in the tumor pathobiology and ...
On day 156, the dog developed diffuse large B-cell lymphoma (DLBCL) of the peripheral lymph nodes. Sequence analysis of the clonally rearranged IgH gene revealed that all neoplastic cells in the spleen, gallbladder, and liver at initial presentation, as well as lymph nodes on da...
New molecular and therapeutic insights into canine diffuse large B-cell lymphoma elucidates the role of the dog as a model for human disease.doi:10.3324/HAEMATOL.2018.207027Luca AresuSerena FerraressoLaura MarconatoLuciano CascioneSara NapoliEugenio Gaudio...
Circulating microRNAs as biomarkers in diffuse large B-cell lymphoma: a pilot prospective longitudinal clinical studyCéline BouvyAdeline WannezChristian ChatelainJean-Michel Dogne22nd Congress of European Hematology Association