Introduction: Juvenile traumatic brain injury (TBI) has the potential to leave patients with a lifetime of consequences that may manifest as cognitive, somatic, and emotional symptoms.Most juvenile TBI is diffuse in nature, and effective treatments remain sparse.The neurovascular unit (NVU) is ...
This constellation of symptoms had historically been called a brainstem contusion in the era prior to MRI. Most comatose patients who appear to show brainstem dysfunction after closed head injury have really suffered DAI. The appearance of DAI on CT scans depends upon the severity of the injury ...
Mounting evidence indicates that brain injury, even moderate injury, can lead to lifetime of physical and mental health symptoms. Therefore, the purpose of this mini-review is to discuss how recovery from traumatic brain injury (TBI) depends on age-at-injury and how aging with a TBI affects....
Brain perfusion imaging (SPECT-Tc-99m HM-PAO) in diagnosis of diffuse axonal injury Patients with diffuse axonal injury (DAI) may present an array of neurologic and psychologic symptoms. Magnetic resonance imaging (MRI) and computed tomogr... W Marks,B Brockhuis,P Lass,... - 《Neurosurgery...
and decerebration. This constellation of symptoms had been called “brainstem contusion” in the era before MRI, and although isolated brainstem contusion can certainly occur, it is extremely rare. Instead, most patients in coma who appear to have brainstem dysfunction after closed head injury have...
Determining regions of altered brain physiology after diffuse brain injury is challenging. Microglia, brain immune cells with ramified and dynamically moving processes, constantly surveil the parenchyma for dysfunction which, when present, results in a changed morphology. Our purpose was to define the sp...
Cognitive impairment, often due to attentional deficits, is a primary driver of disability after traumatic brain injury. It remains unclear whether attenti... SB Snider,G Natalie,HJ Freeman,... - 《Brain Communications》 被引量: 0发表: 2024年 Behavioral and psychiatric symptoms after focal brain...
University of Satilde;o Paulo Medical School, Satilde;o Paulo, Brazil Background: Diffuse axonal injury (DAI), a common cause of neurological sequelae in patients with traumatic brain injury (TBI), is considered one of the most prevalent forms of primary neuronal injury in patients with severe...
First, despite the relatively poor concordance of rat and human miRNA data, in both species, miRNA profiles clearly distinguish all cases of brain injury from uninjured, age-matched controls across all acute and chronic post-injury intervals. Notably, the unequivocal identification of human TBI survi...
Related to Diffuse sclerosis: diffuse sclerodermaSchilder's disease [shil´derz] a subacute or chronic leukoencephalopathy of children and adolescents, closely related to adrenoleukodystrophy, with massive destruction of the white matter of the cerebral hemispheres; clinical symptoms include blindness, de...