Step-by-Step DifferentiationGeorge Beck
et al. Generation of induced neuronal cells by the single reprogramming factor ASCL1. Stem Cell Rep. 3, 282–296 (2014). Article CAS Google Scholar Zhang, Y. et al. Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron 78, 785–798 (2013). Article...
The first step in developing a differentiation strategy is assessing what makes your business unique. Capitalize on that knowledge to help your business stand out, especially in saturated markets such as natural skin care, hospitality, or candle making. Start by completing a checklist of all your ...
对于任意已经参数化数据类型的C++函数模板，只要能够绕过或截获cmath中基础数学函数如sin(x),log(x)的调用，便能顺利编译通过并求出导数。而后将求导应用扩展至矩阵模板，利用李代数实现对特殊正交群(Special Orthogonal Group)的自动求导。为验证自动求导功能，本文使用该接口求取代价函数(Cost Function)的一阶雅可比...
C. A step-by-step workflow for low-level analysis of single-cell RNA-seq data with Bioconductor. F1000Res 5, 2122 (2016). PubMed PubMed Central Google Scholar Butler, A., Hoffman, P., Smibert, P., Papalexi, E. & Satija, R. Integrating single-cell transcriptomic data across ...
Pancreatic β cells differentiated from stem cells provide promise for cell replacement therapy of diabetes. Human pluripotent stem cells could be differentiated into definitive endoderm, followed by pancreatic progenitors, and then subjected to endocrin
There are many other ways to independently verify the numerical gradient, such as dual numbers or the complex step derivative. Another method is to compare the numerical output against a well-known implementation, such as TensorFlow. We plan to conduct a more thorough comparison of numerical accura...
If the discretization step Δx has any significance, A must by multiplied and B divided by Δx. Usually this is not necessary, because only a value that is proportional to the derivative is needed. Now the restricted least-squares solution to the problem can be found by minimizing (10)‖...
Hematopoietic proliferation and differentiation is sustained by a pool of multipotent self-renewing hematopoietic stem cells (HSCs), which give rise to a hierarchy of progenitor populations (HPCs) with more restricted lineage potential, ultimately leading to the production of all types of mature blood...
Pyruvate kinase M2 isoform (PKM2) catalyzes the final, irreversible committed step of glycolysis and is highly expressed in cancer cells. Available studies have shown that PKM2 promotes tumor anabolic metabolism, survival, and proliferation by its intrinsic lower pyruvate kinase activity in the ...