Differentiation of SH-SY5Y cells to neuroblastoma and their neurophysiological responsesAbbaszadeh, Mortezazgün, Alpncü, Gülahin, MeryemGaripcan, BoraSaybal, HaleAnatomy: International Journal of Experimental & Clinical Anatomy
100 ppm of SiO 2 TM nanoparticle had no significant difference on the viability of either undifferentiated or differentiating SH-SY5Y cells. Neurite outgrowth in differentiating cells for 48 h exposure of 100 ppm SiO 2 TM nanoparticle was not significantly changed. Thus, SiO 2 TM nanoparticle ...
LBs are heterogeneous structures composed of protein and lipid molecules and their main constituent is the presynaptic protein α-synuclein. SH-SY5Y cells are neuroblastoma cells commonly used to model PD because they express dopaminergic markers and α-synuclein and they can be differentiated into ...
However, the expression of dopamine receptor D2 ( DRD2 ) gene was markedly increased (p<0.05) in differentiated cells with 3% serum and RA only when compared to undifferentiated cells. In conclusion, to terminally differentiate SH-SY5Y cells to be used as a cell-based model to study ...
Human SH-SY5Y neuroblastoma cells maintain their potential for differentiation and regression in culture conditions. The induction of differentiation could serve as a strategy to inhibit cell proliferation and tumor growth. Previous studies have shown that differentiation of SH-SY5Y cells can be induced ...
LBs are heterogeneous structures composed of protein and lipid molecules and their main constituent is the presynaptic protein α-synuclein. SH-SY5Y cells are neuroblastoma cells commonly used to model PD because they express dopaminergic markers and α-synuclein and they can be differentiated into ...
In this work, we investigated the effect of transient heat shock at 42 °C on the nuclear and cytoplasmic stiffness of SH-SY5Y neuroblastoma cells through atomic force microscopy. Moreover, the variations in the expression of β-tubulin isotypes as a heat shock response were also monitored. ...
Inhibition of MAST1 expression by RNA interference attenuated neuronal differentiation of SH‐SY5Y cells. Cell cycle analyses revealed that MAST1‐depleted cells did not undergo cell cycle arrest after RA treatment. Consistent with this observation, the number of EdU‐positive cells significantly ...
NF-κB/Rel Proteins Are Required for Neuronal Differentiation of SH-SY5Y Neuroblastoma Cells The expression, cellular localization, and activation of the NF-kappaB/Rel transcription factors are altered during neuronal differentiation, but the signi... ZW Feng,AG Porter - 《Journal of Biological Chemis...
2B null cells, we found that long genes and genes expressed at a high level in WT SH-SY5Y cells were disproportionately dependent on TOP2B. Notably, TOP2B null SH-SY5Y cells upregulated mesenchymal markers vimentin (VIM) and fibronectin (FN1) and components of the NOTCH signalling pathway. ...