suitability of cultured cells for successful transplantation in vivo can be reduced quite simply to whether hematopoietic stem cells can be maintained in vitro, or, to state the question as a practical problem, to the development of methods of culture that enable hematopoietic stem cells to ...
Cell differentiation is the process by which specialised cells such as muscle, skin or nerve cells, are formed from less specialised cells such as stem cells and their progenitors. Differentiation occurs during development of an organism to produce new specialised cells, and also in adults to reple...
Integrins in human cells and tumors Ismo Virtanen, ... Victor E. Gould 11 December 1990 View PDF Research articleFull text access Multiple ligand binding functions for VLA-2 α2β1and VLA-3 (α3β1) in the integrin family Martin E. Hemler, ... Nariaki Matsuura ...
Cell differentiation and cell sorting in the development of the cellular slime moulds. II. Reconstitution of the migrating slug by separate cells. It was previously shown that differentiation of the prespore cell in the pseudoplasmodium (slug) of the cellular slime molds is characterized by the sy...
Differentiation may refer to physical and chemical organization of subcellular components or to changes in the structure and organization of cells leading to specialized organs. Control of Embryonic Chemical Development Protein syntheses during oogenesis and embryogenesis are guided by nuclear and nucleolar ...
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Dysfunction of pancreatic δ cells contributes to the etiology of diabetes. Despite their important role, human δ cells are scarce, limiting physiological studies and drug discovery targeting δ cells. To date, no directed δ-cell differentiation method has been established. Here, we demonstrate that...
Embryonic development is a prime example of cell differentiation. During this period embryonic stem cellsdifferentiateinto the threegerm layers: theectoderm, themesoderm, and theendoderm. Cells in the ectoderm differentiate to form tissues such as the skin,brain, and nerves. Cells in the mesoderm, ...
of particular sets of genes that dictate the morphology and function for each cell type. During development, many cells in multicellular organisms can differentiate into other cell types in a tightly regulated manner to ensure the adequate function and stability of cells (Chal and Pourquié, 2017)...
Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells di...