The initial aim of the present study was the derivation of equivalent stem cells from an established and experimentally accessible non-human primate model, the common marmoset monkey (Callithrix jacchus). However, an essential prerequisite in the absence of transgenic reporters in primates and man is...
In vitro assays were conducted using human breast cancer cell lines with lentiviral overexpression of miR-221/-222. Results: In tumour tissues, miR-221/-222 were associated with the occurrence of distant metastases. In particular, high levels of miR-221 were revealed to have a high prognostic ...
have been identified as critical regulators of gene expression necessary to maintain pluripotency and self-renewal in both human and mouse somatic cells [14,15,16]. In addition, transient ectopic expression of such transcription factors is sufficient to reprogram somatic cells back to pluripotency [17...
in Human DiseaseAdipose Tissue and Metabolic DiseaseAdvance in Ca2+ HomeostasisAdvanced Research in Oral OncologyAdvances in Adipose-Derived Stem/Stromal Cell-Based Therapies from the Perspectives of the Bench and the BedsideAdvances in Antithrombotic Research: From Pharmacological Mechanisms to Innovative ...
protein profiling; data-independent acquisition mass spectrometry; SWATH; human stromal/mesenchymal stem cells; differentiation markers; machine learning1. Introduction Bone marrow stromal cells (MSCs) were first detected by Friedenstein in murine bone marrow cultures [1] and subsequently gained enormous ...
host miRNAs;HIV-1 and HIV-2 infection;modulation of host factors 1. Introduction Human immunodeficiency virus type 1 and 2 (HIV-1 and HIV-2) are closely related retroviruses that share 30%–60% overall genetic homology and similar structural and genomic organization [1]. In addition to struct...
Putative functional targets of these miRNAs include genes involved in signal transduction, metabolism, development and cell death. Keywords: host miRNAs; HIV-1 and HIV-2 infection; modulation of host factors 1. Introduction Human immunodeficiency virus type 1 and 2 (HIV-1 and HIV-2) are closely...