According to the biased-competition theory46, when two stimuli compete for representation within a given brain region they do so in a mutually inhibitory manner. The stimulus that "wins" and becomes preferentially represented is the one that is biased either by stimulus properties or by top-down ...
We then performed DE analysis using the bulk RNA-seq data for LUAD from The Cancer Genome Atlas (TCGA)42 comprising 493 cancer and 53 normal samples. The corresponding cumulative scores for the known disease genes were also represented in Fig. 6a–c. Remarkably, DE analysis of epithelial cell...
For a full selection of probe foot prints please refer toApplication Note AP146. Easy to use CITS impedance test systems are exceptionally easy to use. Powerful Windows-based software automates every aspect of testing, enabling the entire process to be controlled by a single click of a mouse...
The normal pulse voltammetry technique uses a series of potential pulses of increasing amplitude. At the end of each pulse, the current is measured. This measurement is usually taken in stationary medium and under unstirred conditions at a dropping mercury electrode (normal pulse polarography) or so...
and analysis of the ultrastructure by electron microscopy revealed a normal organization of sarcomeres (Fig.2f–i; Supplementary Fig.5a, b). As DNM2, together with BIN1, are known to be main players in T-tubule formation and maintenance, we studied T-tubule orientation using potassium ferrocyan...
The best responses obtained with the use of DPV, compared tonormal pulse voltammetry, are on solid electrodes[9], especially those involving organic compounds. Since they are usually adsorbed by the electrode, it is possible that a differential technique discriminates the effects that are more or...
Retinal ganglion cell (RGC) death is the final consequence of many blinding diseases, where there is considerable variation in the time course and severity of RGC loss. Indeed, this process appears to be influenced by a wide variety of genetic and enviro
Finally, the deepest archeological probe of candidate mechanisms that current biomedical science has achieved lies within the now substantial evidence that genetic and/or epigenetic variation may account for DS to aspects of both social and physical environments. Allelic variation within single genes or ...
Despite these modifications, it should be noted that throughout the development of the seizure within the ictal onset zone, there is no current flow to supra-granular cortex, which is surprising considering the canonical organization of the neocortex in which normal pyramidal cells from the infra...
MicroRNAs (miRNAs) packaged into exosomes mediate cell communication and contribute to the pathogenesis of acute type A aortic dissection (ATAAD) with acute lung injury (ALI). The expression profile of plasma exosomal miRNAs in ATAAD patients with ALI hasn’t been identified. We performed a miRNA...