Joint analysis of two related studies of different data types and different study designs using hierarchical modeling in detecting gene-environment interactions.Identifying causal susceptibility alleles for asthma poses many challenges. These include the multigenic nature of the disease, the lack of ...
The multivariable weighted logistic regression models were employed to examine the association between TyG index combinations with obesity indicators and arthritis, and participants in NHANES were further explored the association between TyG index combinations with obesity indicators and arthritis types (RA, ...
Graduate School of Arts and Sciences, Harvard University, Cambridge, MA, USA Tiffany Amariuta Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA Steven Gazal Laboratory for Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan ...
Accordingly, characterizing microbial biomarkers from microbiota profiles has great potential for translational and precision medicine.6 The gut microbiome has been extensively studied over the past years with regards to obesity, while many works have only considered BMI classes in their study designs for...
Furthermore, to make a comprehensive analysis of different types of breast cancer considering the varied PAM50 subtypes and to enhance the reliability of the found outcomes, one more analysis was performed on the GSE45827 dataset64. To dive into detail, PAM50 is one prominent categorization in ...
Dr Berry reported receiving grants from MD Anderson Cancer Center of the University of Texas during the conduct of the study and being co-owner of Berry Consultants LLC, a company that designs bayesian adaptive clinical trials for pharmaceutical and medical device companies, National Institutes of ...
2015, Journal of Clinical Epidemiology Citation Excerpt : Modern clinical and epidemiological studies increasingly rely on longitudinal designs with repeated measurements of prognostic and risk factors during the follow-up, which imply more complex data structures. In the past decade, many studies have ...
Background A diverse range of study designs (e.g. case-control or cohort) are used in the evaluation of adverse effects. We aimed to ascertain whether the risk estimates from meta-analyses of case-control studies differ from that of other study designs. Methods Searches were carried out in ...
In general, randomized research designs are not subject to many biases that affect the weaker forms of evidence obtained from non-randomized studies; however, important deficits in the design, conduct, analysis, and reporting may lead to bias in randomized controlled trials29. According to the ...
Journal of Exposure Science & Environmental Epidemiology volume 33, pages 218–228 (2023)Cite this article 7023 Accesses 18 Citations 1 Altmetric Metrics details Abstract Background Study results are inconclusive regarding how access to greenspace differs by sociodemographic status potentially due to ...