SummaryOBJECTIVE Insulin like growth factor-I (IGF-I) levels in post-menopausal women are reduced by oral administration of the synthetic oestrogen ethinyl oestradiol but increased by transdermal delivery of 17
Previous research has shown that males have a higher likelihood of experiencing irAEs related to neurological, vascular, and pituitary gland issues, while gastrointestinal and haematological irAEs do not show the same gender disparity35. One factor contributing to these differences may be oestrogen, ...
Previously it was always thought that all women needed was either oestrogen or progesterone or both. No one understood the effects of the depletion of the other hormones like testosterone, for example. "When Dr Collins identified the 12 different types he then set about designing 12 separate ...
been the kick up the backside I needed. But I really, really , did not want to start the BP medication. But I have, and so far, so good. I need to lose weight, but apparently, the old depletion of Oestrogen at my age doesn’t help with that at all. Neither does it help with...
Siegfried, J. M. Women and lung cancer: does oestrogen play a role?Lancet Oncol2, 506–513 (2001). ArticleCASPubMedGoogle Scholar Yager, J. D. & Liehr, J. G. Molecular mechanisms of estrogen carcinogenesis.Annu. Rev. Pharmacol. Toxicol.36, 203–232 (1996). ...
M. Women and lung cancer: does oestrogen play a role? Lancet Oncol 2, 506–513 (2001). Article CAS PubMed Google Scholar Yager, J. D. & Liehr, J. G. Molecular mechanisms of estrogen carcinogenesis. Annu. Rev. Pharmacol. Toxicol. 36, 203–232 (1996). Article CAS PubMed Google ...
Incidence rate of cancer is estimated to increase by 40% in 2030. Furthermore, the development of resistance against currently available treatment strategies has contributed to the cancer-associated mortality. Scientists are now looking for the solutions
Co-Expression Effect of SLC7A5/SLC3A2 to Predict Response to Endocrine Therapy in Oestrogen-Receptor-Positive Breast Cancer. Int J Mol Sci. 2020;21:4. Liu et al. BMC Genomics (2021) 22:254 36. Beaumatin F, O'Prey J, Barthet VJA, Zunino B, Parvy JP, Bachmann AM, et al. mTORC1...
Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial Lancet, 381 (9869) (2013), pp. 805-816 View PDFView articleView in ScopusGoogle Scholar [44] H. Staley, I. McCal...
Dose/cycle (and cumulative dosage) is given after the drug name in mg/m2; A60/E90 means 60 mg/m2 of doxorubicin or 90 mg/m2 of epirubicin. iv=intravenous. NS=not significant. ER=oestrogen receptor. IHC=immunohistochemistry. *First four subgroups are as in the forest plots (webappendix ...