These occur for example in the complex bacterial LPS (lipopolysaccharide) structures as well as in other compounds. Here, a Bio-Gel P-2 column eluted only with water at ambient temperature afforded a convenient separation of the main structural types of neutral, charged, or highly polar hexoses...
Therefore, genistein treatment decreases transcription and translation of cytokines by inhibiting NF-κB in LPS-stimulated human monocyte-derived dendritic cells [13]. JAK-STAT/NF-κB pathway modulation Genistein targets JAK/STAT signaling cascade components and prevents activation and nuclear translocation ...
The interaction of Yersinia pseudotuberculosis porin solubilized in deoxycholate with the S- and R-forms of endogenous lipopolysaccharide (LPS) was studied by the quenching of intrinsic protein fluorescence. The samples of S-LPS differed both in the length of O-specific polysaccharide (n = 1 and ...
established a hepatocyte injury and apoptosis model using LPS/D-GalN to investigate the protective effects and mechanisms of MSC-Exos on hepatocyte apoptosis [63]. The results showed that MSC-Exos treatment increased the expression of the autophagy marker proteins LC3-II and Beclin-1, thereby ...
, it can lead to prolonged and unwanted inflammation, causing diseases as cancer, Alzheimer, parkinsonism, multiple sclerosis, pulmonary, liver, enteric, and cardiac diseases [50]. Notably, another alternative interaction, including, TLR3/TLR4 activation by dsRNA or LPS, or detection of viral...
Unexpectedly, TRIM31-positive autophagosomes occurred in Atg5−/− cells and were further increased in Atg5−/− cells treated with LPS stimulation [6]. Further study showed that TRIM31-mediated autophagosomes/autolysosomes formation didn’t need participation of Atg7, Beclin1, and LC3 [6]...
Duan et al (14) have demonstrated that exogenous CGRP attenuates LPS-induced acute lung injury by promoting the expression of markers of M2 macrophages (IL-10, Fizz 1 and mannose receptor C type 1) in primary murine peritoneal macrophages. The underlying mechanism of macrophage polarization toward...
The gut microbiota supplies its host with energy by releasing enzymes and metabolites such as short-chain fatty acids (SCFAs), amino acids, bile acids (BAs), vitamins, succinate, branched-chain amino acids (BCAAs), and lipopolysaccharide (LPS).40,41 In the current study, the biomarker ...
First, we prepared M1 and M2 MW populations from mouse bone marrow-derived MWs (BMDMs) by treatment with IFN-c followed by lipopolysaccharide (LPS) stimulation and by treatment with IL-4, respectively12. Real-time PCR indicated that the BMDM-derived M1 MWs (BM-M1 MWs) expressed significant ...
, it can lead to prolonged and unwanted inflammation, causing diseases as cancer, Alzheimer, parkinsonism, multiple sclerosis, pulmonary, liver, enteric, and cardiac diseases [50]. Notably, another alternative interaction, including, TLR3/TLR4 activation by dsRNA or LPS, or detection of viral...