Loss of function in different polyplotypes of a sample pentaploid genome.Emily BergerDeniz YorukogluJian PengBonnie Berger
www.nature.com/scientificreports OPEN Site-to-site interdomain communication may mediate different loss-of-function received: 03 August 2016 mechanisms in a cancer-associatedaccepted:10February2017 NQO1 polymorphismPublished:14March2017 Encarnación Medina-Carmona1, Jose L. Neira2,3, Eduardo ...
Hence, for this paper, the effect of using many set of lift and drag coefficients versus 1 set of lift and drag coefficients will be evaluated. The second sub-model to be studied is the tip-loss function, so as to account for the differences in the actual flow across the rotor disk ...
While there has been much focus on how mutations can disrupt protein structure and thus cause a loss of function (LOF), alternative mechanisms, specifically dominant-negative (DN) and gain-of-function (GOF) effects, are less understood. Here, we investigate the protein-level effects of ...
For the following reasons stj and stol likely mediate different functions: Stj loss of function is embryonic lethal but an ~ 98% pan-neural RNAi knock down of stol (genotype:elavC155 > stolRNAi; UAS-dcr2) is viable, although it significantly reduces the speed of locomotion (Fig...
Global warming raises serious concerns about the persistence of species and populations locally adapted to their environment, simply because of the shift it produces in their adaptive landscape. For instance, the phenological cycle of tree species may be
asgrief overloadorbereavement overload, this can be one of the more difficult forms of grief to recover from. Compounding loss can result in a feeling of “I just can’t do this anymore.”But with the right therapy and guidance, you can move through all types of grief, including ...
Complete loss of function of the native photoreceptor cells was confirmed using electroretinograms. In the ChR2 transgenic rats, visually evoked potentials were clearly detectable in spite of native photoreceptor function abolishment; however the responses were limited to within blue wavelengths. In ...
Progressive loss of β-cell function leads to worsening glucose tolerance in first-degree relatives of subjects with type 2 diabetes. Diabetes Care 30, 677–682 (2007). Article CAS PubMed Google Scholar Zaharia, O. P. et al. Risk of diabetes-associated diseases in subgroups of patients ...
If you have symptoms of constipation associated with weight loss, or reduced appetite or alternating diarrhea or passage of blood in the stool or dark stools, it is very important that you see your doctor. It could be a sign of something else than just constipation. Constipation...