A different type of genetic therapy: correcting a defective gene using antisense oligonucleotide treatment in CEP290 p.Cys998X LCAdoi:10.1016/j.jaapos.2021.08.021Arlene V. DrackStephen R. RussellArtur V. CideciyanSamuel G. JacobsonBart P. Leroy...
39 Which row shows the normal functions of different types of human stem cells? B Functions Cells that can differentiate Cells that can Cells that can be used for Ainto all types of cells during differentiate into bone the first 3 days of embryo gene therapy to treat ADA-cells in the ...
With the further insights of immunological and gene therapy, the combination of stem cells with other therapies should be actively explored to promote the treatment of POF in the future. Our article may provide guidance and insight for POF animal model selection and new drug development. Graphical...
119. The Effects of Lentiviral Gene Therapy with Bone Morphogenetic Protein-2-Producing Bone Marrow Cells on Spinal Fusion in Rats Rat spinal fusion model. This study aimed to assess the ability of rat bone marrow cells (RBMCs) transfected with bone morphogenetic protein (BMP)-2-contai... M...
Three new trials (MINDACT,35 TAILORx,36 RxPONDER37) have included more than 10 000 patients with ER-positive disease and measurements of gene expression profile who have been randomly allocated chemoendocrine therapy versus the same endocrine therapy alone. Their combined results will be able to...
Regular heavy coffee consumption increases the expression of the CYP1A2 gene, which encodes a member of the cytochrome P450 family of enzymes. Coffee has been found to protect C-allele carriers against breast cancer by reducing breast volume. Coffee consumption has also been shown to slow the ...
Understanding how certain populations differ can "enhance understanding about the features of the disease," according to Huang, as it can help doctors understand how gene therapy could be used as a viable treatment option. "Genetic mutations may occur in one population but not another," Huang sai...
Gene therapy:Aims to introducebeneficial genes or modify existing onesto slow disease progression. Stem cell therapy:Involves transplanting stem cells to replace damaged or lost dopamine-producing neurons. Immunotherapies:Target the protein alpha-synuclein, which accumulates abnormally in Parkinson’s...
Expression of small, therapeutic RNAs in human cell nuclei. Effective intracellular expression of small RNA therapeutics depends on a number of factors. The RNA, whether antisense, ribozyme, or RNA aptamer, must be ... Good,P D,Krikos,... - 《Gene Therapy》 被引量: 357发表: 1997年 Detai...
Gene Therapy Protocols, a volume in the series Methods in Molecular Medicine, is intended to provide scientists with detailed methods to allow them to perf... K. Kozarsky - American Journal of Human Genetics 被引量: 0发表: 1998年 The Aspects of the Use of Rodents in Experimental Research ...