Exosome is a subgroup of extracellular vesicles, which has been serving as an efficient therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes modified with surface decoration and internal therapeutic molecules. After appropriate modification, engineered exosomes are able to de...
with breast cancer showed significantly lower performance on all cognitive domains compared to other patients at the postchemotherapy timepoints.#Although cognitive difficulties are reported during and after chemotherapy for cancer, it seems that there are differences between different types of cancer. We...
Flavonoids like tangeretin and genistein showed important chemosensitization of drug-resistant ovarian cancer cells to different agents like cisplatin and taxane drugs, as well as gemcitabine and topotecan. These natural compounds increased cell death by downregulating the PI3K/Akt pathway [75]. PI3K/...
There is evidence that flavonoids can block metastasis in different types of cancers by suppressing mesenchymal signature molecules and inducing epithelial ones. Quercetin, apigenin and fisetin suppress SNAIL, TWIST, NFκB, and STAT3 (Table1). Various cancer cells are susceptible to the effects of th...
One of the leading causes of death (20.1 per 100,000 women per year), breast cancer is the most prevalent cancer in females. Statistically, 95% of breast cancer are categorized as adenocarcinomas, and 55% of all patients may go into invasive phases; howe
There is evidence that flavonoids can block metastasis in different types of cancers by suppressing mesenchymal signature molecules and inducing epithelial ones. Quercetin, apigenin and fisetin suppress SNAIL, TWIST, NFκB, and STAT3 (Table1). Various cancer cells are susceptible to the effects of th...
MD Anderson has responded by performing genetic testing on several different tumor samples on patients with cancers that are likely to mutate. If the tests show several different strains of cancer, the hospital responds by treating them all. Even so, in those tumor types that MD Anderson has...
We have hypothesized that dietary modulation of intestinal non-coding RNA [microRNA (miRNA)] expression may contribute to the chemoprotective effects of nu... LA Davidson,N Wang,MS Shah,... - 《Carcinogenesis》 被引量: 300发表: 2009年 Determination of DNA adducts of malonaldehyde in humans:...
Disseminated tumor cells (DTCs) in the bone marrow (BM) and circulating tumor cells (CTCs) in blood of breast cancer patients (pts) are known to correlate with worse outcome. Here we demonstrate a different prognostic value of DTCs and CTCs and explain t
Endometrial cancer (EC) is a highly heterogeneous malignancy characterized by varied pathology and prognoses, and the heterogeneity of its cancer cells and the tumor microenvironment (TME) remains poorly understood. We conducted single-cell RNA sequencin