including healthy mammary epithelial cells, primary tumor cells from the right breast, and P7731 cell line (ER-/PR-/HER2-; triple negative bone metastasis breast cancer cell line) was characterized, is used for detecting the upregulated and downregulated genes in different...
with breast cancer showed significantly lower performance on all cognitive domains compared to other patients at the postchemotherapy timepoints.#Although cognitive difficulties are reported during and after chemotherapy for cancer, it seems that there are differences between different types of cancer. We...
Protein-based nanocarriers have demonstrated good potential for cancer drug delivery. Silk sericin nano-particle is arguably one of the best in this field. In this study, we developed a surface charge reversal sericin-based nanocarrier to co-deliver resv
Moderate differences in efficacy between adjuvant chemotherapy regimens for breast cancer are plausible, and could affect treatment choices. We sought any such differences. Methods We undertook individual-patient-data meta-analyses of the randomised trials comparing: any taxane-plus-anthracycline-based regim...
Coffee has different effects on breast cancer for different women. Coffee can increase tamoxifen and reduce chemo treatment effects.
Current cancer treatment offers more options than before, including not just chemotherapy and radiotherapy but also immunotherapy, such as immune checkpoint inhibitors (ICIs). Due to their efficiency and relatively less severe adverse effects compared to certain chemotherapies, ICIs are now approved for...
Triple negative breast cancers (TNBC) account for 10 percent to 20 percent of all breast cancers and tend to be more aggressive than other types of breast cancer. "It's a pretty significant health problem from the standpoint that 11 percent of Caucasians, 17 percent of Hispanics, and 25 per...
There is evidence that flavonoids can block metastasis in different types of cancers by suppressing mesenchymal signature molecules and inducing epithelial ones. Quercetin, apigenin and fisetin suppress SNAIL, TWIST, NFκB, and STAT3 (Table1). Various cancer cells are susceptible to the effects of th...
promoted high anticancer effects of chemo-SDT in target cancer cells. Briefly, engineered exosomes combining with US irradiation not only show high biocompatibility, long blood retention, and precise tumor targeting, but also achieve drug release controllably and no adjacent normal tissue damage. These...
Therefore, in current study, the detailed review of UA therapeutic potential in different cancers is provided that highlighted its role as chemo-preventive and treatment compound for the cancer. Similarly, the mechanism of action of UA in cancers is also brought to limelight that also facilitated ...